Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2229023 | 0.87 | MMP2 (0.45) | MMP2MMP9GRM5GRIN2BENPP2 | |
| SCHEMBL2228696 | 0.87 | MMP2 (0.48) | MMP2MMP9GRIN2BNPC1RAB9A | |
| SCHEMBL2228470 | 0.87 | MMP2 (0.47) | MMP2MMP9GRIN2BENPP2NPC1 | |
| SCHEMBL2228990 | 0.85 | MMP2 (0.46) | MMP2MMP9GRIN2BENPP2NPC1 | |
| SCHEMBL2229360 | 0.84 | MMP2 (0.43) | MMP2MMP9GRIN2B | |
| SCHEMBL2227253 | 0.84 | MMP2 (0.43) | MMP2MMP9GRIN2B | |
| SCHEMBL2362512 | 0.83 | MMP2 (0.43) | MMP2MMP9GRIN2BMEN1KMT2A | |
| SCHEMBL2286530 | 0.82 | MMP2 (0.41) | MMP2MMP9GRIN2BMGLL | |
| SCHEMBL2228670 | 0.82 | MMP2 (0.45) | MMP2MMP9GRIN2BRAB9AMAPT | |
| SCHEMBL2286508 | 0.80 | MMP2 (0.48) | MMP2MMP9GRIN2BMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105837565-A | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | 赛诺菲 | 2016-08-10 | — | — | CN | claimed |
| CN-105837565-A | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | 赛诺菲 | 2016-08-10 | — | — | CN | disclosed |
| WO-2011089550-A1 | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI AVENTIS (FR) | 2011-07-28 | — | — | WO | disclosed |