Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2228026 | 0.86 | GAA (0.56) | GAAL3MBTL1MEN1KMT2APOLB | |
| SCHEMBL28794976 | 0.73 | GRM5 (0.35) | L3MBTL1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL3668041 | 0.72 | GAA (1.00) | GAAL3MBTL1MEN1KMT2APOLB | |
| SCHEMBL664938 | 0.71 | GAA (0.85) | GAAL3MBTL1MEN1KMT2APOLB | |
| SCHEMBL27818229 | 0.71 | GAA (0.85) | GAAL3MBTL1MEN1KMT2APOLB | |
| SCHEMBL2227702 | 0.71 | GAA (0.65) | GAAL3MBTL1MEN1KMT2APOLB | |
| SCHEMBL21104687 | 0.71 | GAA (0.96) | GAAL3MBTL1MEN1KMT2APOLB | |
| SCHEMBL3671016 | 0.71 | GAA (0.96) | GAAL3MBTL1MEN1KMT2APOLB | |
| SCHEMBL3665297 | 0.71 | GAA (0.96) | GAAL3MBTL1MEN1KMT2APOLB | |
| SCHEMBL28091017 | 0.71 | GAA (0.96) | GAAL3MBTL1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011091346-A2 | POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP | BRIDGESTONE CORPORATION (JP) | 2011-07-28 | — | — | WO | disclosed |