Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | ALPI | P09923 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2227259 | 0.86 | GAA (0.55) | GAAL3MBTL1EPHX1LMNAMEN1 | |
| SCHEMBL2276782 | 0.83 | NPC1 (0.41) | GAAL3MBTL1LMNAKMT2ADRD3 | |
| SCHEMBL2228847 | 0.75 | DRD3 (0.39) | DRD3GRM5 | |
| SCHEMBL3668041 | 0.73 | GAA (1.00) | GAAL3MBTL1EPHX1LMNAMEN1 | |
| SCHEMBL27818229 | 0.73 | GAA (0.85) | GAAL3MBTL1EPHX1LMNAMEN1 | |
| SCHEMBL664938 | 0.73 | GAA (0.85) | GAAL3MBTL1EPHX1LMNAMEN1 | |
| SCHEMBL3671016 | 0.72 | GAA (0.96) | GAAL3MBTL1EPHX1LMNAMEN1 | |
| SCHEMBL21104687 | 0.72 | GAA (0.96) | GAAL3MBTL1EPHX1LMNAMEN1 | |
| SCHEMBL3665297 | 0.72 | GAA (0.96) | GAAL3MBTL1EPHX1LMNAMEN1 | |
| SCHEMBL28091017 | 0.72 | GAA (0.96) | GAAL3MBTL1EPHX1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011091346-A2 | POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP | BRIDGESTONE CORPORATION (JP) | 2011-07-28 | — | — | WO | disclosed |