Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2227992 | 0.77 | KDM4E (0.56) | KDM4EGAARAB9ANPC1MAPT | |
| SCHEMBL2562453 | 0.77 | KDM4E (0.54) | KDM4EGAARAB9ANPC1MAPT | |
| SCHEMBL2228132 | 0.75 | KDM4E (0.56) | KDM4EGAARAB9ANPC1MAPT | |
| SCHEMBL15330012 | 0.75 | KDM4E (0.73) | KDM4EGAARAB9ANPC1MAPT | |
| Water SCHEMBL2228975 | 0.74 | KDM4E (0.54) | KDM4EGAARAB9ANPC1MAPT | |
| SCHEMBL2227626 | 0.70 | ALDH1A1 (0.74) | KDM4EGAARAB9ANPC1MAPT | |
| SCHEMBL29952803 | 0.70 | GAA (1.00) | KDM4EGAARAB9AMAPTNPSR1 | |
| SCHEMBL18589547 | 0.70 | ALDH1A1 (0.61) | KDM4EGAARAB9ANPC1MAPT | |
| SCHEMBL15331447 | 0.70 | TBK1 (0.57) | KDM4EGAARAB9ANPC1MAPT | |
| Water SCHEMBL2227396 | 0.69 | ALDH1A1 (0.73) | KDM4EGAARAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011089457-A1 | NOVEL MEDICINAL COMPOUNDS | URATIM GYÁRTÓ KORLÁTOLT FELELŐSSÉGŰ TÁRSASÁG (HU) | 2011-07-28 | — | — | WO | claimed |
| WO-2011089457-A1 | NOVEL MEDICINAL COMPOUNDS | URATIM GYÁRTÓ KORLÁTOLT FELELŐSSÉGŰ TÁRSASÁG (HU) | 2011-07-28 | — | — | WO | disclosed |
| WO-2011089457-A1 | NOVEL MEDICINAL COMPOUNDS | URATIM GYÁRTÓ KORLÁTOLT FELELŐSSÉGŰ TÁRSASÁG (HU) | 2011-07-28 | — | — | WO | disclosed |