Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 1.00 |
| ▸ | RAB9A | P51151 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15332990 | 0.78 | KDM4E (0.64) | GAAKDM4ERAB9AMAPTALDH1A1 | |
| SCHEMBL2559837 | 0.77 | ALDH1A1 (0.67) | GAAKDM4ERAB9AMAPTALDH1A1 | |
| SCHEMBL15329889 | 0.73 | MAPT (1.00) | GAAKDM4ERAB9AMAPTALDH1A1 | |
| SCHEMBL29952952 | 0.70 | MAPT (0.68) | GAAKDM4ERAB9AMAPTALDH1A1 | |
| SCHEMBL2227265 | 0.70 | KDM4E (0.54) | GAAKDM4ERAB9AMAPTALDH1A1 | |
| SCHEMBL2562453 | 0.70 | KDM4E (0.54) | GAAKDM4ERAB9AMAPTALDH1A1 | |
| SCHEMBL2226511 | 0.68 | MAPT (1.00) | GAAKDM4ERAB9AMAPTALDH1A1 | |
| SCHEMBL2227992 | 0.68 | KDM4E (0.56) | GAAKDM4ERAB9AMAPTALDH1A1 | |
| SCHEMBL2230037 | 0.67 | MAPT (0.62) | GAAKDM4ERAB9AMAPTALDH1A1 | |
| SCHEMBL29953106 | 0.67 | MAPT (0.58) | GAAKDM4ERAB9AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |