SCHEMBL2227289

SCHEMBL2227289

Nc1ccccc1-n1c2ccccc2c2cccc(F)c21

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.42
MEN1 O00255 4/20 0.42
KDM4E B2RXH2 3/20 0.42
GAA P10253 3/20 0.42
HTT P42858 2/20 0.42
USP2 O75604 1/20 0.42
TP53 P04637 1/20 0.42
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
ALDH1A1 P00352 5/20 0.37
MAPT P10636 2/20 0.36
ALKBH5 Q6P6C2 1/20 0.35
FTO Q9C0B1 1/20 0.35
DUSP3 P51452 1/20 0.35
HPGD P15428 3/20 0.34
CYP3A4 P08684 2/20 0.34
TSHR P16473 2/20 0.34
HSD17B10 Q99714 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
KEAP1 Q14145 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31322399 1.00 KMT2A (0.42) KMT2AMEN1KDM4EGAAHTT
SCHEMBL2227117 0.84 MEN1 (0.35) KMT2AMEN1KDM4EGAAHTT
SCHEMBL29829673 0.82 GAA (0.54) KMT2AMEN1KDM4EGAAHTT
SCHEMBL29789011 0.82 GAA (0.54) KMT2AMEN1KDM4EGAAHTT
SCHEMBL29442053 0.82 GAA (0.54) KMT2AMEN1KDM4EGAAHTT
SCHEMBL868518 0.82 GAA (0.54) KMT2AMEN1KDM4EGAAHTT
SCHEMBL21148082 0.80 KDM4E (0.42) KMT2AMEN1KDM4EGAAHTT
SCHEMBL11926712 0.80 ALKBH5 (0.50) KDM4ETP53ATML3MBTL1ALDH1A1
SCHEMBL31322402 0.79 USP14 (0.34) KMT2AMEN1KDM4EGAAL3MBTL1
SCHEMBL547459 0.77 L3MBTL1 (0.61) KMT2AMEN1KDM4EHTTATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11812659-B2 Organic electroluminescence device and polycyclic compound for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-07 US disclosed
US-11812659-B2 Organic electroluminescence device and polycyclic compound for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-07 US disclosed
US-20210098715-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2021-04-01 US disclosed
CN-106083848-B For the compound of electronic device 默克专利有限公司 2018-06-19 CN disclosed
US-9708262-B2 Compounds for electronic devices MERCK PATENT GMBH (DE) 2017-07-18 US disclosed
US-9708262-B2 Compounds for electronic devices MERCK PATENT GMBH (DE) 2017-07-18 US disclosed
US-9708262-B2 Compounds for electronic devices MERCK PATENT GMBH (DE) 2017-07-18 US disclosed
CN-106083848-A Compound for electronic device 默克专利有限公司 2016-11-09 CN disclosed
US-20150340613-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2015-11-26 US disclosed
US-20150340613-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2015-11-26 US disclosed
US-8785636-B2 Substituted indoloacridines for organic electroluminescent devices MERCK PATENT GMBH (DE) 2014-07-22 US disclosed
US-20120292576-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2012-11-22 US disclosed
US-20120292576-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2012-11-22 US disclosed
US-20120292576-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2012-11-22 US disclosed
CN-102725268-A Compounds for electronic devices MERCK PATENT GMBH 2012-10-10 CN disclosed
US-20120202997-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2012-08-09 US disclosed
US-20120202997-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2012-08-09 US disclosed
WO-2011088877-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2011-07-28 WO disclosed
WO-2011088877-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2011-07-28 WO disclosed
WO-2011042107-A2 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2011-04-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150340613-A1 COMPOUNDS FOR ELECTRONIC DEVICES SLCO4C1, SLCO1A2, SLCO2A1 KMT2A 2324/4885MEN1 575/4885KDM4E 3073/4885
US-20120202997-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES EPCAM, L1CAM, OR10J3 KMT2A 2479/4885MEN1 470/4885KDM4E 3239/4885
US-20120292576-A1 COMPOUNDS FOR ELECTRONIC DEVICES SLCO4C1, SLCO1A2, SLCO2A1 KMT2A 2324/4885MEN1 575/4885KDM4E 3073/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.