SCHEMBL2227117

SCHEMBL2227117

Nc1ccccc1-n1c2ccc(Br)cc2c2cccc(F)c21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
GAA P10253 3/20 0.35
KDM4E B2RXH2 2/20 0.35
USP2 O75604 1/20 0.35
TP53 P04637 1/20 0.35
HTT P42858 1/20 0.35
JAK2 O60674 1/20 0.33
BTK Q06187 1/20 0.33
RXFP1 Q9HBX9 1/20 0.32
TSPO P30536 1/20 0.32
PTGES O14684 2/20 0.31
GABRP O00591 1/20 0.31
GABRD O14764 1/20 0.31
GABRA1 P14867 1/20 0.31
GABRB1 P18505 1/20 0.31
GABRG2 P18507 1/20 0.31
GABRB3 P28472 1/20 0.31
GABRA5 P31644 1/20 0.31
GABRA3 P34903 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31322399 0.84 KMT2A (0.42) MEN1KMT2AGAAKDM4EUSP2
SCHEMBL2227289 0.84 KMT2A (0.42) MEN1KMT2AGAAKDM4EUSP2
SCHEMBL11926711 0.84 JAK2 (0.38) MEN1KMT2AKDM4ETP53JAK2
SCHEMBL2227508 0.79 LMNA (0.42) KMT2AHTTRXFP1GABRPGABRD
SCHEMBL25686988 0.74 PDE7A (0.35) MEN1KMT2ATSPOMAPTRAD52
SCHEMBL26529975 0.73 GABRA1 (0.43) MEN1KMT2AHTTTSPOPTGES
SCHEMBL17810060 0.73 IDO1 (0.38) MEN1KMT2ATSPOMAPTRAD52
SCHEMBL21148082 0.72 KDM4E (0.42) MEN1KMT2AGAAKDM4EUSP2
SCHEMBL30525340 0.71 DNM1 (0.40) MEN1KMT2AKDM4ETP53TSPO
SCHEMBL26917681 0.71 DNM1 (0.40) MEN1KMT2AKDM4ETP53TSPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116710456-A Compound, light-emitting material, and organic light-emitting element 九州有机光材股份有限公司 2023-09-05 CN disclosed
US-9708262-B2 Compounds for electronic devices MERCK PATENT GMBH (DE) 2017-07-18 US disclosed
US-9708262-B2 Compounds for electronic devices MERCK PATENT GMBH (DE) 2017-07-18 US disclosed
US-9708262-B2 Compounds for electronic devices MERCK PATENT GMBH (DE) 2017-07-18 US disclosed
US-9422287-B2 Bridged triarylamines and -phosphines as materials for electronic devices MERCK PATENT GMBH (DE) 2016-08-23 US disclosed
US-9422287-B2 Bridged triarylamines and -phosphines as materials for electronic devices MERCK PATENT GMBH (DE) 2016-08-23 US disclosed
US-9422287-B2 Bridged triarylamines and -phosphines as materials for electronic devices MERCK PATENT GMBH (DE) 2016-08-23 US disclosed
US-20150340613-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2015-11-26 US disclosed
US-20150340613-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2015-11-26 US disclosed
US-20150340613-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2015-11-26 US disclosed
US-20130026422-A1 BRIDGED TRIARYLAMINES AND -PHOSPHINES AS MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2013-01-31 US disclosed
US-20130026422-A1 BRIDGED TRIARYLAMINES AND -PHOSPHINES AS MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2013-01-31 US disclosed
US-20130026422-A1 BRIDGED TRIARYLAMINES AND -PHOSPHINES AS MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2013-01-31 US disclosed
US-20120292576-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2012-11-22 US disclosed
US-20120292576-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2012-11-22 US disclosed
US-20120292576-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2012-11-22 US disclosed
WO-2011128017-A1 BRIDGED TRIARYLAMINES AND -PHOSPHINES AS MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2011-10-20 WO disclosed
WO-2011128017-A1 BRIDGED TRIARYLAMINES AND -PHOSPHINES AS MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2011-10-20 WO disclosed
WO-2011088877-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2011-07-28 WO disclosed
WO-2011088877-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2011-07-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150340613-A1 COMPOUNDS FOR ELECTRONIC DEVICES SLCO4C1, SLCO1A2, SLCO2A1 MEN1 575/4885KMT2A 2324/4885GAA 2239/4885
US-20130026422-A1 BRIDGED TRIARYLAMINES AND -PHOSPHINES AS MATERIALS FOR ELECTRONIC DEVICES TEC, PNMT, TES MEN1 111/4885KMT2A 221/4885GAA 3401/4885
US-20120292576-A1 COMPOUNDS FOR ELECTRONIC DEVICES SLCO4C1, SLCO1A2, SLCO2A1 MEN1 575/4885KMT2A 2324/4885GAA 2239/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.