SCHEMBL1096218

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL406782	0.92	KEAP1 (0.50)	KEAP1NFE2L2CYP3A4IDO1ALDH1A1
	SCHEMBL3031603	0.83	CYP3A4 (0.52)	KEAP1CYP3A4IDO1ALDH1A1POLB
	SCHEMBL222733	0.83	KEAP1 (0.57)	KEAP1NFE2L2CYP3A4IDO1ALDH1A1
	SCHEMBL31586627	0.83	KEAP1 (0.55)	KEAP1NFE2L2ALDH1A1POLBHPGD
	SCHEMBL21232254	0.82	FADS1 (0.42)	KEAP1NFE2L2ALDH1A1POLBHPGD
	SCHEMBL223134	0.81	KEAP1 (0.53)	KEAP1NFE2L2ALDH1A1POLBHPGD
	SCHEMBL221449	0.81	KEAP1 (0.53)	KEAP1NFE2L2ALDH1A1POLBHPGD
	SCHEMBL27475536	0.80	MAPT (0.53)	CYP3A4ALDH1A1POLBHPGDGAA
	SCHEMBL21232082	0.79	FADS1 (0.37)	KEAP1NFE2L2CYP3A4ALDH1A1POLB
	Potassium SCHEMBL30811379	0.79	KEAP1 (0.52)	KEAP1NFE2L2ALDH1A1POLBHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.