Known targets — ChEMBL curated mechanism
ACVR1ADORA1ADORA2AADORA2BADORA3ESR1ESR2FLT3GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSC1GSK3AGSK3BHRH1HRH2HTR7IDH1IDH2IMPA1IRAK1JAK1JAK2JAK3MEN1OPRM1P2RX3PDE5ASCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASIGMAR1SLC6A2SYKTACR1TOP2ATYK2
The experimentally established mechanism targets of Citric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HMGCR | P04035 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ACLY | P53396 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | CPT2 | P23786 | 1/20 | 0.31 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citric Acid SCHEMBL2227442 | 0.98 | CA4 (0.70) | CA4ALDH1A1HMGCRCHRM1TBXA2R | |
| Citric Acid SCHEMBL5471630 | 0.98 | CA4 (0.76) | CA4ALDH1A1HMGCRCHRM1TBXA2R | |
| Citric Acid SCHEMBL9319655 | 0.95 | CA4 (0.73) | CA4ALDH1A1HMGCRCHRM1TBXA2R | |
| Citric Acid SCHEMBL21569398 | 0.95 | CA4 (0.73) | CA4ALDH1A1HMGCRCHRM1TBXA2R | |
| Citric Acid SCHEMBL2227453 | 0.95 | CA4 (0.73) | CA4ALDH1A1HMGCRCHRM1TBXA2R | |
| Citric Acid SCHEMBL1684057 | 0.95 | CA4 (0.73) | CA4ALDH1A1HMGCRCHRM1TBXA2R | |
| Citric Acid SCHEMBL1301477 | 0.95 | CA4 (0.73) | CA4ALDH1A1HMGCRCHRM1TBXA2R | |
| Citric Acid SCHEMBL21569387 | 0.95 | CA4 (0.73) | CA4ALDH1A1HMGCRCHRM1TBXA2R | |
| Citric Acid SCHEMBL18263181 | 0.95 | CA4 (0.73) | CA4ALDH1A1HMGCRCHRM1TBXA2R | |
| Citric Acid SCHEMBL475574 | 0.95 | CA4 (0.73) | CA4ALDH1A1HMGCRCHRM1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115335353-B | Composition containing hydrogen citrate and dipsilver, process for producing the same, and antibacterial agent or antiviral agent using the same and process for producing the same | 佐佐木化学工业株式会社 | 2023-06-09 | — | — | CN | claimed |
| US-20230089450-A1 | DISILVER HYDROGEN CITRATE-CONTAINING COMPOSITION, METHOD FOR PRODUCING SAME, ANTIBACTERIAL AGENT OR ANTIVIRAL AGENT USING SAME, AND METHOD FOR PRODUCING SAME | SASAKI CHEMICAL INDUSTRY CO., LTD. (JP) | 2023-03-23 | — | — | US | claimed |
| US-11528930-B2 | Short-term wash treatment of produce | SMARTWASH SOLUTIONS, LLC (US) | 2022-12-20 | — | — | US | claimed |
| US-20210244066-A1 | SHORT-TERM WASH TREATMENT OF PRODUCE | SMARTWASH SOLUTIONS, LLC | 2021-08-12 | — | — | US | claimed |
| US-20130171224-A1 | TREATMENT OF BIOFILMS | ADVANCED MEDICAL SOLUTIONS LIMITED (GB) | 2013-07-04 | — | — | US | claimed |
| WO-2011089379-A2 | TREATMENT OF BIOFILMS | ADVANCED MEDICAL SOLUTIONS LIMITED (GB) | 2011-07-28 | — | — | WO | claimed |
| US-12604898-B2 | Disilver hydrogen citrate-containing composition, method for producing same, antibacterial agent or antiviral agent using same, and method for producing same | SASAKI CHEMICAL INDUSTRY CO., LTD. (JP) | 2026-04-21 | — | — | US | disclosed |
| EP-4169899-B1 | DISILVER HYDROGEN CITRATE-CONTAINING COMPOSITION, METHOD FOR PRODUCING SAME, ANTIBACTERIAL AGENT OR ANTIVIRAL AGENT USING SAME, AND METHOD FOR PRODUCING SAME | SASAKI CHEMICAL IND CO LTD (JP) | 2026-04-08 | — | — | EP | disclosed |
| EP-4169899-B1 | DISILVER HYDROGEN CITRATE-CONTAINING COMPOSITION, METHOD FOR PRODUCING SAME, ANTIBACTERIAL AGENT OR ANTIVIRAL AGENT USING SAME, AND METHOD FOR PRODUCING SAME | SASAKI CHEMICAL IND CO LTD (JP) | 2026-04-08 | — | — | EP | disclosed |
| EP-4169899-C0 | DISILVER HYDROGEN CITRATE-CONTAINING COMPOSITION, METHOD FOR PRODUCING SAME, ANTIBACTERIAL AGENT OR ANTIVIRAL AGENT USING SAME, AND METHOD FOR PRODUCING SAME | SASAKI CHEMICAL IND CO LTD (JP) | 2026-04-08 | — | — | EP | disclosed |
| CN-120787966-A | Silver-containing disinfection composition and preparation method and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2025-10-17 | — | — | CN | disclosed |
| EP-4169899-A4 | DISILVER HYDROGEN CITRATE-CONTAINING COMPOSITION, METHOD FOR PRODUCING SAME, ANTIBACTERIAL AGENT OR ANTIVIRAL AGENT USING SAME, AND METHOD FOR PRODUCING SAME | Sasaki Chemical Industry Co., Ltd. (JP) | 2024-06-26 | — | — | EP | disclosed |
| CN-115335353-B | Composition containing hydrogen citrate and dipsilver, process for producing the same, and antibacterial agent or antiviral agent using the same and process for producing the same | 佐佐木化学工业株式会社 | 2023-06-09 | — | — | CN | disclosed |
| EP-4169899-A1 | DISILVER HYDROGEN CITRATE-CONTAINING COMPOSITION, METHOD FOR PRODUCING SAME, ANTIBACTERIAL AGENT OR ANTIVIRAL AGENT USING SAME, AND METHOD FOR PRODUCING SAME | Sasaki Chemical Industry Co., Ltd. (JP) | 2023-04-26 | — | — | EP | disclosed |
| US-20230089450-A1 | DISILVER HYDROGEN CITRATE-CONTAINING COMPOSITION, METHOD FOR PRODUCING SAME, ANTIBACTERIAL AGENT OR ANTIVIRAL AGENT USING SAME, AND METHOD FOR PRODUCING SAME | SASAKI CHEMICAL INDUSTRY CO., LTD. (JP) | 2023-03-23 | — | — | US | disclosed |
| US-20230089450-A1 | DISILVER HYDROGEN CITRATE-CONTAINING COMPOSITION, METHOD FOR PRODUCING SAME, ANTIBACTERIAL AGENT OR ANTIVIRAL AGENT USING SAME, AND METHOD FOR PRODUCING SAME | SASAKI CHEMICAL INDUSTRY CO., LTD. (JP) | 2023-03-23 | — | — | US | disclosed |
| CN-115335353-A | Hydrogen-bis-silver citrate-containing composition and method for producing same, and antibacterial agent or antiviral agent using same and method for producing same | 佐佐木化学工业株式会社 | 2022-11-11 | — | — | CN | disclosed |
| JP-2022164635-A | COMPOSITION CONTAINING DISILVER HYDROGEN CITRATE AND ITS MANUFACTURING METHOD, AS WELL AS ANTIBACTERIAL AGENT OR ANTIVIRAL AGENT USING THE SAME AND ITS MANUFACTURING METHOD | 佐々木化学工業株式会社 | 2022-10-27 | — | — | JP | disclosed |
| US-20130171224-A1 | TREATMENT OF BIOFILMS | ADVANCED MEDICAL SOLUTIONS LIMITED (GB) | 2013-07-04 | — | — | US | disclosed |
| WO-2011089379-A2 | TREATMENT OF BIOFILMS | ADVANCED MEDICAL SOLUTIONS LIMITED (GB) | 2011-07-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12604898-B2 | Disilver hydrogen citrate-containing composition, method for producing same, antibacterial agent or antiviral agent using same, and method for producing same | ACLY, CS, SAMHD1 | CA4 391/4885ALDH1A1 1979/4885HMGCR 925/4885 |
| US-20230089450-A1 | DISILVER HYDROGEN CITRATE-CONTAINING COMPOSITION, METHOD FOR PRODUCING SAME, ANTIBACTERIAL AGENT OR ANTIVIRAL AGENT USING SAME, AND METHOD FOR PRODUCING SAME | CS, ACLY, DAD1 | CA4 128/4885ALDH1A1 2677/4885HMGCR 859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.