Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | EED | O75530 | 1/20 | 0.37 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.37 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.37 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.37 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22277450 | 0.90 | MAPT (0.42) | MAPTKDM4ETHRBGPR119PTPN2 | |
| SCHEMBL22277478 | 0.86 | MAPT (0.39) | MAPTKDM4ETHRBGPR119PTPN2 | |
| SCHEMBL22277482 | 0.83 | DPP4 (0.37) | MAPTKDM4ETHRBGPR119PTPN2 | |
| SCHEMBL22277386 | 0.81 | GPR119 (0.50) | KDM4EGPR119PTPN2PTPN1PTPN6 | |
| SCHEMBL22277447 | 0.80 | TTR (0.35) | — | |
| SCHEMBL24179407 | 0.80 | DPP4 (0.35) | MAPTKDM4ETHRBGPR119PTPN2 | |
| SCHEMBL22277387 | 0.78 | GPR119 (0.49) | KDM4EGPR119PTPN2PTPN1PTPN6 | |
| SCHEMBL27397892 | 0.78 | TTR (0.48) | THRBMEN1KMT2AMAPK1HTT | |
| SCHEMBL30289413 | 0.78 | TTR (0.48) | THRBMEN1KMT2AMAPK1HTT | |
| SCHEMBL22277407 | 0.76 | MEN1 (0.47) | MAPTKDM4ETHRBGPR119PTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200241417-A1 | RESIST COMPOSITION AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2020-07-30 | — | — | US | disclosed |