SCHEMBL22277407

SCHEMBL22277407

CC(C)(C)OC(=O)N1CCC(C(C)(C)OC(=O)c2cccc(I)c2)CC1

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
GPR119 Q8TDV5 7/20 0.47
KDM4E B2RXH2 2/20 0.47
PKM P14618 1/20 0.47
STS P08842 2/20 0.43
MAPT P10636 1/20 0.42
THRB P10828 1/20 0.42
PTPN2 P17706 1/20 0.42
PTPN1 P18031 1/20 0.42
PTPN6 P29350 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22277413 0.89 KDM4E (0.39) MEN1KMT2AGPR119KDM4EPKM
SCHEMBL22277387 0.86 GPR119 (0.49) MEN1KMT2AGPR119KDM4EPKM
SCHEMBL22277445 0.80 TP53BP1 (0.36) MEN1KMT2A
SCHEMBL3301081 0.79 CRBN (0.55) MEN1KMT2AGPR119KDM4EPKM
SCHEMBL22277386 0.79 GPR119 (0.50) MEN1KMT2AGPR119KDM4EPKM
SCHEMBL2284947 0.78 GPR119 (0.55) MEN1KMT2AGPR119KDM4EPKM
SCHEMBL22277450 0.77 MAPT (0.42) MEN1KMT2AGPR119KDM4ESTS
SCHEMBL1417078 0.77 SLC7A5 (0.51)
SCHEMBL30260183 0.77 SLC7A5 (0.51)
SCHEMBL22277391 0.77 GPR119 (0.44) KMT2AGPR119KDM4EPKMMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11835859-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-12-05 US disclosed
US-20230129578-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-04-27 US disclosed
US-20230129578-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-04-27 US disclosed
US-20220004100-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-01-06 US disclosed
US-20200241414-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-07-30 US disclosed
US-20200241417-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-07-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200241414-A1 RESIST COMPOSITION AND PATTERNING PROCESS INSR, HNRNPU, HNRNPR MEN1 2251/4885KMT2A 1882/4885GPR119 191/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.