Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 7/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 7/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10301995 | 0.92 | GABRA1 (0.37) | GABRA1GABRB2SIRT2CNR2NAAA | |
| SCHEMBL12735646 | 0.89 | NAAA (0.38) | GABRA1GABRB2SIRT2NAAAFFAR4 | |
| SCHEMBL12717005 | 0.89 | GABRA1 (0.37) | GABRA1GABRB2SIRT2CNR2FGFR2 | |
| SCHEMBL12740096 | 0.89 | GABRA1 (0.37) | GABRA1GABRB2SIRT2CNR2FGFR2 | |
| SCHEMBL12740172 | 0.87 | FFAR1 (0.36) | SIRT2FFAR4 | |
| SCHEMBL6889160 | 0.86 | GABRA1 (0.43) | GABRA1GABRB2CNR2NAAAFGFR2 | |
| SCHEMBL8932329 | 0.84 | NAAA (0.39) | GABRA1GABRB2NAAAFGFR2FGFR1 | |
| SCHEMBL20803686 | 0.84 | GABRA1 (0.39) | GABRA1GABRB2SIRT2CNR2NAAA | |
| SCHEMBL12740138 | 0.84 | TUBB1 (0.38) | GABRA1GABRB2SIRT2NAAAFFAR4 | |
| SCHEMBL18509967 | 0.84 | FGFR2 (0.39) | GABRA1GABRB2NAAAFGFR2FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200239775-A1 | TETRACYCLIC LIQUID CRYSTAL COMPOUND HAVING DIATOMIC BONDING GROUP AND 2,3-DIFLUOROPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2020-07-30 | — | — | US | disclosed |