Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR2 | P21802 | 2/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13264329 | 0.92 | TUBB1 (0.40) | FGFR2FGFR1TUBB1GABRA1GABRB2 | |
| SCHEMBL18509966 | 0.86 | PTGS2 (0.40) | TUBB1ALOX5APFEN1PTGS2PTGS1 | |
| SCHEMBL12739567 | 0.85 | TUBB1 (0.50) | FGFR2FGFR1TUBB1KDM4EKMT2A | |
| SCHEMBL12736528 | 0.85 | TACR2 (0.40) | TUBB1GABRA1GABRB2PKMNAAA | |
| SCHEMBL12740940 | 0.84 | TACR2 (0.42) | FGFR2FGFR1GABRA1GABRB2PKM | |
| SCHEMBL12736487 | 0.84 | TACR2 (0.42) | FGFR2FGFR1GABRA1GABRB2PKM | |
| SCHEMBL20739050 | 0.84 | FGFR2 (0.43) | FGFR2FGFR1TUBB1GABRA1GABRB2 | |
| SCHEMBL22277696 | 0.84 | GABRA1 (0.39) | FGFR2FGFR1TUBB1GABRA1GABRB2 | |
| SCHEMBL12717609 | 0.84 | FFAR1 (0.39) | PKMKDM4EGAAPTGS2ALDH1A1 | |
| SCHEMBL21609904 | 0.83 | FGFR2 (0.44) | FGFR2FGFR1PTPRCALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10400169-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2019-09-03 | — | — | US | disclosed |
| US-20180030350-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2018-02-01 | — | — | US | disclosed |
| US-20170044438-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2017-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170044438-A1 | LIQUID-CRYSTALLINE MEDIUM | VIM, COL2A1, COL1A1 | FGFR2 386/4885FGFR1 70/4885TUBB1 918/4885 |
| US-20180030350-A1 | LIQUID-CRYSTALLINE MEDIUM | VIM, COL2A1, COL1A1 | FGFR2 386/4885FGFR1 70/4885TUBB1 918/4885 |
| US-10400169-B2 | Liquid-crystalline medium | VIM, COL2A1, COL1A1 | FGFR2 386/4885FGFR1 70/4885TUBB1 918/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.