Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CD38 | P28907 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12018227 | 0.75 | NOX1 (0.44) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL25003335 | 0.74 | BLM (0.46) | CD38MAPTBLM | |
| SCHEMBL9998918 | 0.73 | HPGDS (0.41) | ALDH1A1PKMMAPTHTT | |
| SCHEMBL7119064 | 0.72 | MAPT (0.49) | ALDH1A1MAPTHTT | |
| SCHEMBL21988033 | 0.71 | AAK1 (0.43) | TNIK | |
| SCHEMBL2469763 | 0.71 | CYP19A1 (0.43) | ALDH1A1PKMMAPT | |
| SCHEMBL22094785 | 0.71 | GRM4 (0.54) | CD38ALDH1A1BLM | |
| SCHEMBL24001003 | 0.70 | MDM2 (0.52) | CD38HTT | |
| Imidazole-1-Carboxylic Acid Phenylamide SCHEMBL10668282 | 0.69 | RAB9A (0.50) | ALDH1A1PKMHTT | |
| SCHEMBL10662756 | 0.69 | GAA (0.45) | CA12CA1CA2CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020151756-A1 | STABLE SOLID DISPERSIONS OF B-RAF KINASE DIMER INHIBITOR, METHODS OF PREPARATION, AND USES THEREFOR | BEIGENE, LTD. (KY) | 2020-07-30 | — | — | WO | disclosed |