Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.42 |
| ▸ | CD38 | P28907 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 4/20 | 0.39 |
| ▸ | KCNJ6 | P48051 | 3/20 | 0.39 |
| ▸ | KCNJ5 | P48544 | 3/20 | 0.39 |
| ▸ | KCNJ3 | P48549 | 3/20 | 0.39 |
| ▸ | LCK | P06239 | 2/20 | 0.39 |
| ▸ | FYN | P06241 | 2/20 | 0.39 |
| ▸ | CSF1R | P07333 | 2/20 | 0.39 |
| ▸ | LYN | P07948 | 2/20 | 0.39 |
| ▸ | KIT | P10721 | 2/20 | 0.39 |
| ▸ | SRC | P12931 | 2/20 | 0.39 |
| ▸ | FLT4 | P35916 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7119064 | 0.82 | MAPT (0.49) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL1614574 | 0.80 | HTT (0.43) | NPC1RAB9AMAPTLMNA | |
| SCHEMBL22094785 | 0.80 | GRM4 (0.54) | BLMGRM4CD38MEN1KMT2A | |
| SCHEMBL26923056 | 0.78 | HTR2C (0.41) | NPC1RAB9AMEN1KMT2A | |
| SCHEMBL10662282 | 0.76 | KMT2A (0.53) | CD38NPC1RAB9AMEN1KMT2A | |
| SCHEMBL11767236 | 0.76 | KMT2A (0.56) | GRM4CD38NPC1RAB9AMEN1 | |
| SCHEMBL24001003 | 0.76 | MDM2 (0.52) | CD38RAB9AMEN1KMT2A | |
| SCHEMBL28161149 | 0.75 | LMNA (0.54) | GRM4NPC1RAB9AMEN1KMT2A | |
| SCHEMBL1613423 | 0.75 | PIK3C3 (0.41) | MEN1KMT2AMAPT | |
| Imidazole-1-Carboxylic Acid Phenylamide SCHEMBL10668282 | 0.74 | RAB9A (0.50) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230045421-A1 | SUBSTITUTED ARYLMETHYLUREAS AND HETEROARYLMETHYLUREAS, ANALOGUES THEREOF, AND METHODS USING SAME | ARBUTUS BIOPHARMA CORP (CA) | 2023-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230045421-A1 | SUBSTITUTED ARYLMETHYLUREAS AND HETEROARYLMETHYLUREAS, ANALOGUES THEREOF, AND METHODS USING SAME | HAVCR2, HMBS, AHCY | BLM 240/4885GRM4 4030/4885CD38 1177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.