Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | BRAF | P15056 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | BCR | P11274 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7126842 | 0.82 | MAPT (0.47) | MAPTLMNAKMT2AMEN1ATM | |
| SCHEMBL25003335 | 0.82 | BLM (0.46) | MAPTLMNAKMT2AMEN1RAB9A | |
| SCHEMBL1614574 | 0.79 | HTT (0.43) | MAPTLMNARAB9ANPC1HTT | |
| SCHEMBL25395355 | 0.77 | KDM4E (0.43) | MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL24001003 | 0.77 | MDM2 (0.52) | KMT2AMEN1RAB9AHTTL3MBTL1 | |
| SCHEMBL28161149 | 0.77 | LMNA (0.54) | MAPTLMNAKMT2AMEN1RAB9A | |
| SCHEMBL26923056 | 0.76 | HTR2C (0.41) | KMT2AMEN1RAB9ANPC1BRAF | |
| SCHEMBL7117612 | 0.76 | MAPT (0.45) | MAPTLMNAKMT2AMEN1ATM | |
| SCHEMBL1613423 | 0.76 | PIK3C3 (0.41) | MAPTKMT2AMEN1ALDH1A1HTT | |
| Imidazole-1-Carboxylic Acid Phenylamide SCHEMBL10668282 | 0.75 | RAB9A (0.50) | ALDH1A1RAB9ANPC1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030105142-A1 | Amide derivatives useful as inhibitors of the production of cytokines | ASTRAZENECA AB | 2003-06-05 | — | — | US | claimed |
| US-4749729-A | MONO- AND DI-IMIDAZOLE CARBOXAMIDES | AMERICAN CYANAMID COMPANY (US) | 1988-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105142-A1 | Amide derivatives useful as inhibitors of the production of cytokines | IL6, IL6ST, IL2 | MAPT 4663/4885LMNA 2338/4885KMT2A 3225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.