Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | GSR | P00390 | 2/20 | 0.35 |
| ▸ | IGF1R | P08069 | 3/20 | 0.33 |
| ▸ | SELL | P14151 | 2/20 | 0.33 |
| ▸ | SELP | P16109 | 2/20 | 0.33 |
| ▸ | SELE | P16581 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31542040 | 0.79 | GSR (0.39) | TRPA1GSRIGF1RSELLSELP | |
| SCHEMBL23750505 | 0.76 | GSR (0.44) | GSRIGF1RSELLSELPSELE | |
| SCHEMBL1173818 | 0.71 | TRPA1 (0.56) | TRPA1SELLSELPSELEHPGD | |
| SCHEMBL2226886 | 0.69 | PTGS2 (0.58) | MEN1GAAKMT2AALDH1A1POLB | |
| SCHEMBL2233917 | 0.69 | KDM4E (0.52) | SELLSELPHPGDMAPK1LMNA | |
| SCHEMBL23750511 | 0.67 | LMNA (0.39) | IGF1RSELLSELPSELEHPGD | |
| SCHEMBL1179394 | 0.65 | TRPA1 (0.54) | TRPA1IGF1RHPGDMAPK1NPC1 | |
| SCHEMBL3962866 | 0.65 | SELL (0.39) | TRPA1SELLSELPSELEHPGD | |
| SCHEMBL22249384 | 0.64 | MAPT (0.41) | SELLSELPSELEHPGDMAPK1 | |
| SCHEMBL28401269 | 0.64 | HPGD (0.41) | TRPA1SELLSELPSELEHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011085454-A1 | GP120 -BINDING BENZENE COMPOUNDS AND SACCHARIDE COMPOUNDS | KATHOLIEKE UNIVERSITEIT LEUVEN K.U.LEUVEN R&D (BE) | 2011-07-21 | — | — | WO | disclosed |