Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | SELL | P14151 | 3/20 | 0.39 |
| ▸ | SELP | P16109 | 3/20 | 0.39 |
| ▸ | SELE | P16581 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31542040 | 0.73 | GSR (0.39) | LMNAALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL11408792 | 0.72 | CA1 (0.52) | LMNAALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL20692746 | 0.71 | IDH1 (0.38) | LMNAALDH1A1POLBGAAALOX15 | |
| SCHEMBL23750505 | 0.70 | GSR (0.44) | HTTSELLSELPSELEIGF1R | |
| SCHEMBL22249281 | 0.68 | MAPT (0.64) | LMNAALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL1173818 | 0.67 | TRPA1 (0.56) | LMNAKDM4EPOLBGAATDP1 | |
| SCHEMBL2228043 | 0.67 | TRPA1 (0.36) | LMNAALDH1A1MAPTPOLBGAA | |
| SCHEMBL31542039 | 0.65 | MEP1B (0.40) | LMNAALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL29369616 | 0.64 | BCL2 (0.47) | LMNAALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL68262 | 0.64 | ACHE (0.55) | LMNAALDH1A1MAPTKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155864-A1 | COMPOUNDS AND PHARMACEUTICAL USES THEREOF | SYNEURX INTERNATIONAL (TAIWAN) CORP. (CN) | 2021-08-12 | — | — | WO | disclosed |