Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22280476 | 0.75 | AURKA (0.45) | — | |
| SCHEMBL22280630 | 0.72 | GRM5 (0.41) | DHFR | |
| SCHEMBL22265486 | 0.68 | F10 (0.35) | IGF1R | |
| SCHEMBL22265485 | 0.68 | F10 (0.35) | IGF1R | |
| SCHEMBL22280554 | 0.68 | KDM4E (0.41) | — | |
| SCHEMBL22265325 | 0.67 | HTT (0.38) | IGF1R | |
| SCHEMBL3849741 | 0.60 | SORT1 (0.45) | — | |
| SCHEMBL21914358 | 0.59 | TAAR1 (0.44) | — | |
| SCHEMBL13874386 | 0.58 | NPC1 (0.49) | — | |
| SCHEMBL12067104 | 0.58 | ALDH1A1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020154431-A1 | INHIBITORS OF SPINSTER HOMOLOG 2 (SPNS2) FOR USE IN THERAPY | LYNCH KEVIN R (US) | 2020-07-30 | — | — | WO | disclosed |