Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | TPMT | P51580 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22280538 | 0.76 | TTR (0.42) | TTRGABRA1GABRB1GABRB2ERN1 | |
| SCHEMBL7152837 | 0.69 | ADRA2A (0.38) | TTRGABRA1GABRB1GABRB2 | |
| SCHEMBL21263766 | 0.67 | GABRA1 (0.56) | TTRGABRA1GABRB1GABRB2 | |
| SCHEMBL22403150 | 0.67 | TTR (0.34) | TTRGABRA1GABRB1GABRB2 | |
| SCHEMBL17161274 | 0.64 | GABRA1 (0.41) | TTRGABRA1GABRB1GABRB2 | |
| SCHEMBL25479340 | 0.63 | — | — | |
| SCHEMBL19985768 | 0.63 | GPR17 (0.33) | TPMT | |
| Formaldehyde SCHEMBL28061059 | 0.62 | TTR (0.45) | TTRERN1TPMT | |
| SCHEMBL27106654 | 0.61 | HDAC3 (0.39) | TTRERN1TPMT | |
| SCHEMBL21159415 | 0.61 | TTR (0.59) | TTRGABRA1GABRB1GABRB2ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024040745-A1 | AMIDE COMPOUND CONTAINING IODO ARYL OR IODO HETEROARYL, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 科睿驰（深圳）医疗科技发展有限公司 | 2024-02-29 | — | — | WO | disclosed |