Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.56 |
| ▸ | MEN1 | O00255 | 9/20 | 0.56 |
| ▸ | POLB | P06746 | 6/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16291379 | 0.70 | MAPT (0.62) | MAPTKMT2AMEN1POLBL3MBTL1 | |
| SCHEMBL16291381 | 0.70 | MAPT (0.62) | MAPTKMT2AMEN1POLBL3MBTL1 | |
| SCHEMBL29518135 | 0.70 | MAPT (0.77) | MAPTKMT2AMEN1POLBL3MBTL1 | |
| SCHEMBL12112134 | 0.70 | MAPT (0.77) | MAPTKMT2AMEN1POLBL3MBTL1 | |
| SCHEMBL29518137 | 0.70 | MAPT (0.77) | MAPTKMT2AMEN1POLBL3MBTL1 | |
| SCHEMBL19654561 | 0.69 | KDM4E (0.61) | MAPTKMT2AMEN1POLBL3MBTL1 | |
| SCHEMBL2556095 | 0.68 | LDHA (0.72) | MAPTKMT2AMEN1POLBL3MBTL1 | |
| SCHEMBL28372353 | 0.67 | SIRT5 (1.00) | MAPTKMT2AMEN1POLBL3MBTL1 | |
| SCHEMBL12113861 | 0.67 | GAA (0.87) | MAPTKMT2AMEN1POLBL3MBTL1 | |
| SCHEMBL28373468 | 0.66 | SIRT5 (0.81) | MAPTKMT2AMEN1POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200240995-A1 | KDAC VARIANTS AND USES THEREOF | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2020-07-30 | — | — | US | disclosed |