Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.33 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22282242 | 0.85 | DNM1 (0.40) | DNM1CA1CA2CA12CA9 | |
| SCHEMBL22281707 | 0.78 | TDP1 (0.42) | SMN1; SMN2HSD17B10TDP1ALDH1A1USP2 | |
| SCHEMBL12363095 | 0.78 | HSD17B10 (0.42) | HSD17B10TDP1ALDH1A1PAOX | |
| SCHEMBL10243682 | 0.77 | EPHX1 (0.48) | DNM1CA1CA2CA12CA9 | |
| SCHEMBL12012184 | 0.76 | HSD17B10 (0.41) | HSD17B10TDP1ALDH1A1CYP1A2PAOX | |
| SCHEMBL12093782 | 0.74 | ACHE (0.57) | — | |
| SCHEMBL13484350 | 0.74 | ECE1 (0.39) | HTTHSD17B10TDP1NPSR1PRMT1 | |
| SCHEMBL21499 | 0.74 | DNM1 (0.43) | DNM1CA1CA2CA12CA9 | |
| SCHEMBL16682368 | 0.73 | TDP1 (0.38) | HSD17B10TDP1ALDH1A1 | |
| SCHEMBL12295177 | 0.73 | TDP1 (0.38) | HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020154447-A1 | MTORC MODULATORS AND USES THEREOF | AEOVIAN PHARMACEUTICALS, INC. (US) | 2020-07-30 | — | — | WO | disclosed |