Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5412050 | 0.77 | CA4 (0.39) | LTA4HTSHRCA4KCNA3CA5A | |
| SCHEMBL2230239 | 0.72 | LTA4H (0.35) | LTA4HTSHRCA4KCNA3LMNA | |
| SCHEMBL27882572 | 0.67 | LTA4H (0.45) | LTA4HTSHRCA4CA1CA2 | |
| SCHEMBL6840036 | 0.67 | LTA4H (0.45) | LTA4HTSHRCA4CA1CA2 | |
| SCHEMBL275159 | 0.66 | LTA4H (0.50) | LTA4HTSHRCA4CA1CA2 | |
| SCHEMBL9716178 | 0.64 | TSHR (0.36) | LTA4HTSHRCA4KCNA3CA5A | |
| SCHEMBL27512397 | 0.64 | LTA4H (0.41) | LTA4HTSHRCA4CA1CA2 | |
| SCHEMBL1782417 | 0.62 | THRB (0.38) | LTA4HTSHRKCNA3CA5ACA5B | |
| SCHEMBL2354326 | 0.62 | CA4 (0.48) | LTA4HTSHRCA4CA1CA2 | |
| SCHEMBL7694976 | 0.62 | LTA4H (0.45) | LTA4HTSHRCA4CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0447066-B2 | Pneumatic tyres | BRIDGESTONE CORP (JP) | 2000-08-16 | — | — | EP | claimed |
| US-5409969-A | Comprising silica filler, carbon black, silane coupler, living polymer of butadiene-styrene | BRIDGESTONE CORPORATION (JP) | 1995-04-25 | — | — | US | claimed |
| EP-0447066-A1 | Pneumatic tyres | Bridgestone Corporation (JP) | 1991-09-18 | — | — | EP | claimed |
| US-5017636-A | Also containing polyisoprene, natural rubber, butadiene-styrene copolymer, wear and heat resistance, resilience | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1991-05-21 | — | — | US | claimed |
| EP-1721930-B1 | RUBBER COMPOSITION | JSR CORP (JP) | 2015-01-28 | — | — | EP | disclosed |
| US-7981966-B2 | Rubber composition | JSR CORPORATION (JP) | 2011-07-19 | — | — | US | disclosed |
| US-20070208126-A1 | Vulcanizable rubber composition, in particular for low rolling resistance treads of vehicle tires | PIRELLI PNEUMATICI S.P.A. | 2007-09-06 | — | — | US | disclosed |
| US-20070185267-A1 | Rubber composition | JSR CORPORATION (JP) | 2007-08-09 | — | — | US | disclosed |
| EP-1721930-A1 | RUBBER COMPOSITION | JSR Corporation (JP) | 2006-11-15 | — | — | EP | disclosed |
| US-20040220324-A1 | First modified conjugated diolefin-vinylaromatic copolymer; second conjugated diolefin-vinylaromatic copolymer; first carbon black-based reinforcing filler; second silica-based reinforcing filler | PIRELLI PNEUMATICI S.P.A. | 2004-11-04 | — | — | US | disclosed |
| EP-0972790-B1 | Process for producing a vulcanizable rubber composition including carbon black-based and silicia-based reinforcing fillers | PIRELLI (IT) | 2004-09-22 | — | — | EP | disclosed |
| EP-1189767-B1 | LOW ROLLING RESISTANCE TIRE FOR VEHICLES | PIRELLI (IT) | 2004-07-28 | — | — | EP | disclosed |
| EP-0934973-A1 | Vulcanizable rubber composition, in particular for low rolling resistance treads of vehicle tires | PIRELLI PNEUMATICI S.p.A. (IT) | 1999-08-11 | — | — | EP | disclosed |
| US-5496883-A | COMPRISING TREAD RUBBER OF POLYBUTADIENE POLYMER OR COPOLYMER CONTAINING SILICA AND MODIFIED WITH SILANE COUPLING AGENT; COUPLING AGENT; WET SKID RESISTANCE, LOW ROLLLING RESISTANCE | BRIDGESTONE CORPORATION (JP) | 1996-03-05 | — | — | US | disclosed |
| US-5409969-A | Comprising silica filler, carbon black, silane coupler, living polymer of butadiene-styrene | BRIDGESTONE CORPORATION (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0299074-B1 | TIRE | Bridgestone Corporation (JP) | 1992-01-29 | — | — | EP | disclosed |
| US-5066721-A | TIRES MADE OF SILICA FILLED, SILANE MODIFIED RUBBER | BRIDGESTONE CORPORATION (JP) | 1991-11-19 | — | — | US | disclosed |
| EP-0447066-A1 | Pneumatic tyres | Bridgestone Corporation (JP) | 1991-09-18 | — | — | EP | disclosed |
| US-5017636-A | Also containing polyisoprene, natural rubber, butadiene-styrene copolymer, wear and heat resistance, resilience | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1991-05-21 | — | — | US | disclosed |
| EP-0299074-A1 | TIRE | Bridgestone Corporation (JP) | 1989-01-18 | — | — | EP | disclosed |