Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.31 |
| ▸ | TGM2 | P21980 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5135539 | 0.67 | KMT2A (0.32) | TSHRLTA4HTHRBKCNA3 | |
| SCHEMBL1782417 | 0.67 | THRB (0.38) | TSHRLTA4HALDH1A1THRBL3MBTL1 | |
| SCHEMBL275159 | 0.66 | LTA4H (0.50) | TSHRLTA4HALDH1A1CA4TDP1 | |
| SCHEMBL2170644 | 0.64 | CA4 (0.34) | TSHRLTA4HALDH1A1CA4 | |
| SCHEMBL22654269 | 0.64 | CYP3A4 (0.36) | TSHRLTA4HALDH1A1THRBKCNA3 | |
| SCHEMBL1781213 | 0.64 | ALDH1A1 (0.39) | TSHRLTA4HALDH1A1THRBL3MBTL1 | |
| SCHEMBL2228212 | 0.64 | SRC (0.37) | TSHRLTA4HALDH1A1CA4KCNA3 | |
| SCHEMBL2228207 | 0.64 | LTA4H (0.36) | TSHRLTA4HCA4KCNA3CA5A | |
| SCHEMBL7694976 | 0.62 | LTA4H (0.45) | TSHRLTA4HALDH1A1CA4TDP1 | |
| SCHEMBL6840036 | 0.62 | LTA4H (0.45) | TSHRLTA4HALDH1A1CA4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299074-B1 | TIRE | Bridgestone Corporation (JP) | 1992-01-29 | — | — | EP | disclosed |
| US-5066721-A | TIRES MADE OF SILICA FILLED, SILANE MODIFIED RUBBER | BRIDGESTONE CORPORATION (JP) | 1991-11-19 | — | — | US | disclosed |
| EP-0299074-A1 | TIRE | Bridgestone Corporation (JP) | 1989-01-18 | — | — | EP | disclosed |