Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP2E1 | P05181 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP2C8 | P10632 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.35 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | PRKCH | P24723 | 1/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LATS1 | O95835 | 1/20 | 0.31 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | AOC1 | P19801 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18626328 | 0.82 | PRKCH (0.34) | CYP1A2CYP2E1CYP3A4CYP2C8CYP2D6 | |
| SCHEMBL22043381 | 0.79 | PRKCH (0.33) | CYP1A2CYP2E1CYP3A4CYP2C8CYP2D6 | |
| SCHEMBL682267 | 0.77 | TRPA1 (0.37) | CYP1A2CYP2E1CYP3A4CYP2C8CYP2D6 | |
| SCHEMBL18626327 | 0.74 | PRKCH (0.34) | CYP1A2CYP2E1CYP3A4CYP2C8CYP2D6 | |
| SCHEMBL20113126 | 0.74 | TSHR (0.35) | PRKCHPRKCEPRKCQPRKCDALDH1A1 | |
| SCHEMBL31291226 | 0.74 | TDP1 (0.38) | CYP1A2CYP2E1CYP3A4CYP2C8CYP2D6 | |
| SCHEMBL30947593 | 0.74 | ALDH1A1 (0.38) | CYP1A2CYP3A4PRKCHPRKCEPRKCQ | |
| SCHEMBL27842129 | 0.74 | TDP1 (0.38) | CYP1A2CYP2E1CYP3A4CYP2C8CYP2D6 | |
| SCHEMBL25564526 | 0.72 | CA12 (0.43) | CYP1A2CYP2E1CYP2C8CYP2D6CYP2A6 | |
| SCHEMBL1311356 | 0.71 | ALDH1A1 (0.45) | CYP1A2TRPA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020154499-A1 | SULFONIMIDAMIDE COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-07-30 | — | — | WO | disclosed |