Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 2/20 | 0.37 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | LATS1 | O95835 | 2/20 | 0.35 |
| ▸ | LATS2 | Q9NRM7 | 2/20 | 0.35 |
| ▸ | PRKCH | P24723 | 1/20 | 0.34 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27842129 | 0.82 | TDP1 (0.38) | TRPA1SIRT3TDP1ALOX5PTGS1 | |
| SCHEMBL31291226 | 0.82 | TDP1 (0.38) | TRPA1SIRT3TDP1ALOX5PTGS1 | |
| SCHEMBL30947593 | 0.82 | ALDH1A1 (0.38) | TRPA1SIRT3TDP1PTGS1PTGS2 | |
| SCHEMBL179265 | 0.81 | SIRT3 (0.41) | TRPA1KIF11SIRT3TDP1ALOX5 | |
| SCHEMBL1705592 | 0.80 | KIF11 (0.39) | KIF11TDP1ALOX5PTGS1PTGS2 | |
| SCHEMBL1311356 | 0.79 | ALDH1A1 (0.45) | TRPA1KIF11ALDH1A1CYP1A2CYP17A1 | |
| SCHEMBL18626328 | 0.79 | PRKCH (0.34) | TRPA1SIRT3TDP1LATS1LATS2 | |
| SCHEMBL18626327 | 0.79 | PRKCH (0.34) | TRPA1SIRT3TDP1LATS1LATS2 | |
| SCHEMBL20576799 | 0.78 | KIF11 (0.38) | KIF11ALOX5PTGS1PTGS2ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL29243632 | 0.77 | ALDH1A1 (0.44) | TRPA1KIF11ALDH1A1CYP1A2CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 183 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12030853-B2 | MASP-2 inhibitors and methods of use | OMEROS CORPORATION (US) | 2024-07-09 | — | — | US | disclosed |
| US-12030853-B2 | MASP-2 inhibitors and methods of use | OMEROS CORPORATION (US) | 2024-07-09 | — | — | US | disclosed |
| US-20240207273-A1 | TREATMENT OF AUTISM SPECTRUM DISORDERS, OBSESSIVE-COMPULSIVE DISORDER AND ANXIETY DISORDERS | RUGEN HOLDINGS (CAYMAN) LIMITED (KY) | 2024-06-27 | — | — | US | disclosed |
| US-20230355617-A1 | SMALL MOLECULE INHIBITORS OF LEMUR TYROSINE KINASE 3 | THE UNIVERSITY OF SUSSEX (GB) | 2023-11-09 | — | — | US | disclosed |
| US-20230357254-A1 | IMIDAZOPYRIDAZINES AS MODULATORS OF IL-17 | JANSSEN PHARMACEUTICA NV (BE) | 2023-11-09 | — | — | US | disclosed |
| US-20230355617-A1 | SMALL MOLECULE INHIBITORS OF LEMUR TYROSINE KINASE 3 | THE UNIVERSITY OF SUSSEX (GB) | 2023-11-09 | — | — | US | disclosed |
| US-20230348508-A1 | METAL COMPLEX, ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME, AND CONSUMER PRODUCT | BEIJING BAYI SPACE LIQUID CRYSTAL TECHNOLOGY CO. LTD. (CN) | 2023-11-02 | — | — | US | disclosed |
| US-20230339900-A1 | CASEIN KINASE 1 DELTA MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2023-10-26 | — | — | US | disclosed |
| US-20230337517-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2023-10-19 | — | — | US | disclosed |
| US-20230337517-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2023-10-19 | — | — | US | disclosed |
| US-20070027321-A1 | Bipyridyl amines and ethers as modulators of metabotropic glutamate receptor-5 | MERCK SHARP & DOHME CORP. | 2007-02-01 | — | — | US | disclosed |
| WO-1997035049-A1 | ELECTROPLATING SOLUTION AND METHOD OF DEPOSITING SEMI-BRIGHT NICKEL PLATE FROM THE SOLUTION | BASF AKTIENGESELLSCHAFT (DE) | 1997-09-25 | — | — | WO | disclosed |
| EP-0610236-B1 | PROCESS FOR MAKING NICKEL-PLATED CASTINGS | BASF AG (DE) | 1995-09-20 | — | — | EP | disclosed |
| EP-0621908-B1 | PROCESS FOR PRODUCING NICKEL-PLATED MOULDINGS | BASF AG (DE) | 1995-09-06 | — | — | EP | disclosed |
| US-5445727-A | Having two brighteners; a heterocyclic quaternary ammonium salt and a substituted acetylenic compound | BASF AKTIENGESELLSCHAFT (DE) | 1995-08-29 | — | — | US | disclosed |
| US-5438140-A | Using cyclic ammonium compounds as brighteners | BASF AKTIENGESELLSCHAFT (DE) | 1995-08-01 | — | — | US | disclosed |
| EP-0621908-A1 | PROCESS FOR PRODUCING NICKEL-PLATED MOULDINGS. | BASF AG (DE) | 1994-11-02 | — | — | EP | disclosed |
| EP-0610236-A1 | PROCESS FOR MAKING NICKEL-PLATED CASTINGS. | BASF AG (DE) | 1994-08-17 | — | — | EP | disclosed |
| WO-1993015241-A1 | PROCESS FOR PRODUCING NICKEL-PLATED MOULDINGS | BASF AKTIENGESELLSCHAFT (DE) | 1993-08-05 | — | — | WO | disclosed |
| WO-1993009275-A1 | PROCESS FOR MAKING NICKEL-PLATED CASTINGS | BASF AKTIENGESELLSCHAFT (DE) | 1993-05-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357254-A1 | IMIDAZOPYRIDAZINES AS MODULATORS OF IL-17 | IL17A, IL23R, IL15 | TRPA1 2567/4885KIF11 4462/4885SIRT3 411/4885 |
| US-20230339900-A1 | CASEIN KINASE 1 DELTA MODULATORS | CSNK1D, CSNK1A1, CSNK2A1 | TRPA1 3866/4885KIF11 1892/4885SIRT3 2731/4885 |
| US-20230355617-A1 | SMALL MOLECULE INHIBITORS OF LEMUR TYROSINE KINASE 3 | LMTK3, LMTK2, LIMK1 | TRPA1 1496/4885KIF11 2168/4885SIRT3 701/4885 |
| US-20070027321-A1 | Bipyridyl amines and ethers as modulators of metabotropic glutamate receptor-5 | GRM5, GRIK5, GRM1 | TRPA1 798/4885KIF11 2678/4885SIRT3 4601/4885 |
| US-20230337517-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | LBR, OCIAD2, OCIAD1 | TRPA1 659/4885KIF11 3361/4885SIRT3 1097/4885 |
| US-20240207273-A1 | TREATMENT OF AUTISM SPECTRUM DISORDERS, OBSESSIVE-COMPULSIVE DISORDER AND ANXIETY DISORDERS | GRIN2A, GRIN1, GRIN2B | TRPA1 1344/4885KIF11 3852/4885SIRT3 4094/4885 |
| US-20230348508-A1 | METAL COMPLEX, ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME, AND CONSUMER PRODUCT | TRPM5, TRPM6, TRPM2 | TRPA1 9/4885KIF11 3075/4885SIRT3 1769/4885 |
| US-12030853-B2 | MASP-2 inhibitors and methods of use | MASP2, METAP2, SPINT2 | TRPA1 4840/4885KIF11 3394/4885SIRT3 4158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.