Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCH | P24723 | 1/20 | 0.34 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LATS1 | O95835 | 3/20 | 0.32 |
| ▸ | LATS2 | Q9NRM7 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22043381 | 0.85 | PRKCH (0.33) | PRKCHPRKCEPRKCQPRKCDTRPA1 | |
| SCHEMBL16477946 | 0.84 | SIRT3 (0.36) | PRKCHPRKCEPRKCQPRKCDCYP1A2 | |
| SCHEMBL18626327 | 0.84 | PRKCH (0.34) | PRKCHPRKCEPRKCQPRKCDTRPA1 | |
| SCHEMBL22282113 | 0.82 | CYP1A2 (0.35) | PRKCHPRKCEPRKCQPRKCDTRPA1 | |
| SCHEMBL13412862 | 0.80 | ALOX5 (0.36) | LATS1LATS2CA12CA1CA2 | |
| SCHEMBL682267 | 0.79 | TRPA1 (0.37) | PRKCHPRKCEPRKCQPRKCDTRPA1 | |
| SCHEMBL22140201 | 0.78 | TP53 (0.34) | CYP3A4LATS1LATS2CA12CA1 | |
| SCHEMBL17403402 | 0.78 | CNR1 (0.35) | LATS1LATS2CA12CA1CA2 | |
| SCHEMBL18626326 | 0.78 | LOXL2 (0.41) | PRKCHPRKCEPRKCQPRKCDLATS1 | |
| SCHEMBL22140281 | 0.78 | PRKCH (0.32) | PRKCHPRKCEPRKCQPRKCDTRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9593095-B2 | Methods for the treatment of bacterial infections | DUKE UNIVERSITY (US) | 2017-03-14 | — | — | US | disclosed |