Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | CASP1 | P29466 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 2/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3654298 | 0.84 | CASP1 (0.37) | GAAMAPTKDM4ECASP1ALDH1A1 | |
| SCHEMBL6816261 | 0.79 | MAPT (0.40) | GAAMAPTKDM4ECASP1ALDH1A1 | |
| SCHEMBL6535756 | 0.76 | TDP1 (0.39) | GAAMAPTCASP1ALDH1A1TDP1 | |
| SCHEMBL6535654 | 0.75 | TDP1 (0.48) | GAAMAPTKDM4EALDH1A1TDP1 | |
| SCHEMBL28252731 | 0.74 | CASP1 (0.42) | GAAMAPTCASP1ALDH1A1TDP1 | |
| SCHEMBL29433029 | 0.74 | CASP1 (0.42) | GAAMAPTCASP1ALDH1A1TDP1 | |
| SCHEMBL33893 | 0.74 | CASP1 (0.42) | GAAMAPTCASP1ALDH1A1TDP1 | |
| SCHEMBL6535648 | 0.73 | POLB (0.43) | MAPTKDM4ECASP1ALDH1A1TDP1 | |
| SCHEMBL6486185 | 0.73 | CASP1 (0.41) | GAAMAPTCASP1ALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL10534032 | 0.73 | CASP1 (0.41) | GAAMAPTKDM4ECASP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3687970-A1 | PARA-PHENYLENEDIAMINE BASES WITH AN ALIPHATIC CHAINE AND TRIALKYL AMMONIUM GROUP, AND THE USE OF SAME FOR OXIDATION DYEING KERATIN FIBRES | L'Oreal (FR) | 2020-08-05 | — | — | EP | disclosed |