Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6535756 | 0.89 | TDP1 (0.39) | POLBCYP3A4ALDH1A1MEN1NPC1 | |
| SCHEMBL11510925 | 0.86 | POLB (0.43) | POLBKDM4EMAOBMAOAADRA2A | |
| SCHEMBL6535654 | 0.85 | TDP1 (0.48) | KDM4EMAOBMAOACYP3A4TP53 | |
| SCHEMBL3968067 | 0.83 | CYP3A4 (0.42) | POLBKDM4EMAOBMAOAADRA2A | |
| SCHEMBL11311588 | 0.82 | POLB (0.47) | POLBKDM4EMAOBMAOAADRA2A | |
| SCHEMBL6535617 | 0.82 | CHRNB2 (0.39) | POLBALDH1A1MEN1TDP1LMNA | |
| SCHEMBL6535758 | 0.80 | ALDH1A1 (0.37) | POLBCYP3A4ALDH1A1NPC1RAB9A | |
| SCHEMBL6535506 | 0.80 | GAA (0.33) | POLBALDH1A1MEN1NPC1KMT2A | |
| SCHEMBL3654298 | 0.76 | CASP1 (0.37) | POLBKDM4ECYP3A4TP53ALDH1A1 | |
| Benzene SCHEMBL27545048 | 0.75 | ANPEP (0.41) | POLBMAOACYP3A4TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1359887-A4 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P & G CLAIROL INC (US) | 2004-08-18 | — | — | EP | disclosed |
| US-6673932-B2 | Primary intermediates for oxidative coloration of hair | THE PROCTER & GAMBLE COMPANY | 2004-01-06 | — | — | US | disclosed |
| EP-1359887-A1 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P&G-Clairol, Inc. (US) | 2003-11-12 | — | — | EP | disclosed |
| US-20030131422-A1 | Primary intermediates for oxidative coloration of hair | WELLA OPERATIONS US, LLC | 2003-07-17 | — | — | US | disclosed |
| WO-2002058658-A1 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P&G - CLAIROL, INC. (US) | 2002-08-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030131422-A1 | Primary intermediates for oxidative coloration of hair | CYC1, MT-CO1, COX5A | POLB 378/4885KDM4E 3202/4885MAOB 340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.