Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.34 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6535654 | 0.91 | TDP1 (0.48) | TDP1MAPK1ALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL6535648 | 0.89 | POLB (0.43) | TDP1TSHRALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL6535758 | 0.86 | ALDH1A1 (0.37) | TDP1TSHRALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL6535506 | 0.86 | GAA (0.33) | TDP1TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL3969449 | 0.82 | ALOX5 (0.41) | TDP1TSHRMAPK1ALDH1A1CYP3A4 | |
| SCHEMBL6535896 | 0.79 | KDM4E (0.45) | TSHRMAPK1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL3654298 | 0.79 | CASP1 (0.37) | TDP1TSHRMAPK1ALDH1A1CYP3A4 | |
| SCHEMBL6535617 | 0.78 | CHRNB2 (0.39) | TDP1ALDH1A1MEN1POLB | |
| SCHEMBL22283000 | 0.76 | GAA (0.37) | TDP1TSHRMAPK1ALDH1A1CYP3A4 | |
| SCHEMBL11510925 | 0.75 | POLB (0.43) | TDP1TSHRMAPK1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1359887-A4 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P & G CLAIROL INC (US) | 2004-08-18 | — | — | EP | disclosed |
| US-6673932-B2 | Primary intermediates for oxidative coloration of hair | THE PROCTER & GAMBLE COMPANY | 2004-01-06 | — | — | US | disclosed |
| EP-1359887-A1 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P&G-Clairol, Inc. (US) | 2003-11-12 | — | — | EP | disclosed |
| US-20030131422-A1 | Primary intermediates for oxidative coloration of hair | WELLA OPERATIONS US, LLC | 2003-07-17 | — | — | US | disclosed |
| WO-2002058658-A1 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P&G - CLAIROL, INC. (US) | 2002-08-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030131422-A1 | Primary intermediates for oxidative coloration of hair | CYC1, MT-CO1, COX5A | TDP1 1998/4885TSHR 3593/4885MAPK1 403/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.