Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28252731 | 0.83 | CASP1 (0.42) | CASP1TP53HTTALDH1A1CYP3A4 | |
| SCHEMBL33893 | 0.83 | CASP1 (0.42) | CASP1TP53HTTALDH1A1CYP3A4 | |
| SCHEMBL29433029 | 0.83 | CASP1 (0.42) | CASP1TP53HTTALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL10534032 | 0.81 | CASP1 (0.41) | CASP1TP53HTTALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL10534025 | 0.81 | CASP1 (0.41) | CASP1TP53HTTALDH1A1CYP3A4 | |
| SCHEMBL446559 | 0.79 | ALDH1A1 (0.41) | CASP1HTTALDH1A1CYP3A4TDP1 | |
| SCHEMBL29940754 | 0.79 | ALDH1A1 (0.41) | CASP1HTTALDH1A1CYP3A4TDP1 | |
| Benzene SCHEMBL27545048 | 0.79 | ANPEP (0.41) | CASP1LMNATP53HTTALDH1A1 | |
| SCHEMBL22101860 | 0.79 | CASP1 (0.39) | CASP1TP53ALDH1A1CYP3A4TDP1 | |
| SCHEMBL4620368 | 0.79 | CASP1 (0.39) | CASP1TP53ALDH1A1CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1239467-C | Primary intermediates for oxidative dyeing of hair | P & G CLAIROL INC (US) | 2006-02-01 | — | — | CN | disclosed |
| US-6951574-B2 | Primary intermediates for oxidative coloration of hair | THE PROCTER & GAMBLE COMPANY (US) | 2005-10-04 | — | — | US | disclosed |
| US-20040255403-A1 | Primary intermediates for oxidative coloration of hair | LIM MU-ILL (US) | 2004-12-23 | — | — | US | disclosed |
| US-6800097-B2 | FOR DYEING KERATIN FIBERS; HAIR DYES | WELLA AKTIENGESELLSCHAFT (DE) | 2004-10-05 | — | — | US | disclosed |
| US-6780998-B2 | DEVELOPER-COUPLER SUBSTANCE COMBINATION HAIR DYES | WELLA AKTIENGESELLSCHAFT (DE) | 2004-08-24 | — | — | US | disclosed |
| US-6780999-B2 | Primary intermediates for oxidative coloration of hair | THE PROCTER & GAMBLE COMPANY | 2004-08-24 | — | — | US | disclosed |
| CN-1486297-A | Primary intermediates for oxidative dyeing of hair | P&G | 2004-03-31 | — | — | CN | disclosed |
| EP-1353895-A2 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P&G-Clairol, Inc. (US) | 2003-10-22 | — | — | EP | disclosed |
| US-20030070241-A1 | Substituted 2-aminoalkyl-1,4-Diaminobenzene compounds and oxidation dye precursor compositions containing same | WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) | 2003-04-17 | — | — | US | disclosed |
| US-20020189033-A1 | Substituted 2-aminoalkyl-1,4diaminobenzene compounds and oxidation dye precursor compositions containing same | WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) | 2002-12-19 | — | — | US | disclosed |
| US-20020144357-A1 | Primary intermediates for oxidative coloration of hair | WELLA OPERATIONS US, LLC | 2002-10-10 | — | — | US | disclosed |
| US-6436152-B1 | Substituted 2-aminoalky-1,4-diaminobenzene compounds and oxidation dye precursor compositions containing same | WELLA AKTIENGESELLSCHAFT (DE) | 2002-08-20 | — | — | US | disclosed |
| WO-2002058632-A2 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P&G-CLARIOL, INC. (US) | 2002-08-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040255403-A1 | Primary intermediates for oxidative coloration of hair | COX5A, CYC1, MT-CO1 | CASP1 651/4885LMNA 1878/4885TP53 1789/4885 |
| US-20020189033-A1 | Substituted 2-aminoalkyl-1,4diaminobenzene compounds and oxidation dye precursor compositions containing same | DDT, CYP1B1, ALDH7A1 | CASP1 794/4885LMNA 3367/4885TP53 2610/4885 |
| US-20030070241-A1 | Substituted 2-aminoalkyl-1,4-Diaminobenzene compounds and oxidation dye precursor compositions containing same | DDT, ALDH7A1, DDC | CASP1 672/4885LMNA 3052/4885TP53 2678/4885 |
| US-20020144357-A1 | Primary intermediates for oxidative coloration of hair | COX5A, CYC1, MT-CO1 | CASP1 651/4885LMNA 1878/4885TP53 1789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.