Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28085134 | 0.81 | CDK1 (0.45) | LMNARAB9A | |
| SCHEMBL11252782 | 0.74 | LMNA (0.53) | LMNACYP19A1MEN1CYP3A4CYP2D6 | |
| SCHEMBL29020379 | 0.74 | ALDH1A1 (0.49) | LMNACYP19A1MEN1CYP3A4CYP2D6 | |
| SCHEMBL28879340 | 0.73 | ABCG2 (0.42) | LMNACYP19A1MEN1CYP3A4KMT2A | |
| SCHEMBL17503283 | 0.72 | NPC1 (0.45) | CYP19A1MEN1CYP3A4KMT2ANPC1 | |
| SCHEMBL4129050 | 0.72 | CDK1 (0.47) | LMNACYP3A4KDM4EALDH1A1 | |
| SCHEMBL29204371 | 0.71 | CYP19A1 (0.42) | CYP19A1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL28513252 | 0.71 | CYP19A1 (0.46) | CYP19A1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL28840935 | 0.71 | CYP19A1 (0.46) | CYP19A1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL22283272 | 0.70 | LMNA (0.54) | LMNACYP19A1MEN1CYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11559512-B2 | Composition for prevention, alleviation, and/or treatment of heat illness | TOYO UNIVERSITY (JP) | 2023-01-24 | — | — | US | disclosed |
| US-20200297694-A1 | COMPOSITION FOR PREVENTION, ALLEVIATION, AND/OR TREATMENT OF HEAT ILLNESS | TOYO UNIVERSITY (JP) | 2020-09-24 | — | — | US | disclosed |
| EP-3689345-A1 | COMPOSITION FOR PREVENTION, ALLEVIATION, AND/OR TREATMENT OF HEAT STROKE | Toyo University (JP) | 2020-08-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11559512-B2 | Composition for prevention, alleviation, and/or treatment of heat illness | TNF, HSF1, HSP90AA1 | LMNA 2092/4885CYP19A1 1409/4885MEN1 3508/4885 |
| US-20200297694-A1 | COMPOSITION FOR PREVENTION, ALLEVIATION, AND/OR TREATMENT OF HEAT ILLNESS | TNF, HSF1, HSP90AA1 | LMNA 2092/4885CYP19A1 1409/4885MEN1 3508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.