Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | PREP | P48147 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | CTSC | P53634 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23630151 | 0.96 | ALDH1A1 (0.56) | ALDH1A1HTR2CHTR2BPREPMEN1 | |
| SCHEMBL7360933 | 0.87 | HTR2C (0.48) | ALDH1A1HTR2CHTR2BPREPMEN1 | |
| Proline SCHEMBL28412300 | 0.84 | ALDH1A1 (0.54) | ALDH1A1HTR2CHTR2BPREPMEN1 | |
| SCHEMBL9464997 | 0.82 | ALDH1A1 (0.58) | ALDH1A1HTR2CHTR2BPREPMEN1 | |
| SCHEMBL9464553 | 0.82 | ALDH1A1 (0.58) | ALDH1A1HTR2CHTR2BPREPMEN1 | |
| SCHEMBL3447413 | 0.82 | TSHR (0.51) | ALDH1A1HTR2CHTR2BTSHRGAA | |
| SCHEMBL4758450 | 0.82 | TSHR (0.51) | ALDH1A1HTR2CHTR2BTSHRGAA | |
| SCHEMBL489770 | 0.82 | TSHR (0.51) | ALDH1A1HTR2CHTR2BTSHRGAA | |
| SCHEMBL630517 | 0.81 | TSHR (0.63) | ALDH1A1HTR2CHTR2BTSHRGAA | |
| SCHEMBL693351 | 0.81 | TSHR (0.63) | ALDH1A1HTR2CHTR2BTSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113845563-A | FAP alpha enzyme activated podophyllotoxin derivative and preparation method and application thereof | 遵义医药高等专科学校 | 2021-12-28 | — | — | CN | claimed |
| US-20020147317-A1 | Fluorogenic compounds and uses therefor | 3M INNOVATIVE PROPETIES COMPANY | 2002-10-10 | — | — | US | claimed |
| US-6372895-B1 | USEFUL IN ASSAYING FOR BIOLOGICAL ACTIVITY | 3M INNOVATIVE PROPERTIES COMPANY | 2002-04-16 | — | — | US | claimed |
| EP-0416282-B1 | Microbiologically produced N-Acyl-L-proline-acylase, process for its production and its use | DEGUSSA (DE) | 1994-09-14 | — | — | EP | claimed |
| US-5219741-A | Reacting in the presence of microbiologically produced N-acyl-L-proline acylase | DEGUSSA AG (DE) | 1993-06-15 | — | — | US | claimed |
| US-5120652-A | Synthesis of proline from acyl derivatives; thermostable | DEGUSSA AG (DE) | 1992-06-09 | — | — | US | claimed |
| EP-0416282-A1 | Microbiologically produced N-Acyl-L-proline-acylase, process for its production and its use | Degussa Aktiengesellschaft (DE) | 1991-03-13 | — | — | EP | claimed |
| JP-1074987-A | — | — | None | — | — | JP | disclosed |
| CN-112714649-B | Cyclic dinucleotide derivatives and antibody drug conjugates thereof | 第一三共株式会社 | 2024-07-02 | — | — | CN | disclosed |
| CN-113845563-B | FAP alpha enzyme activated podophyllotoxin derivative and preparation method and application thereof | 遵义医药高等专科学校 | 2024-02-20 | — | — | CN | disclosed |
| CN-113845563-A | FAP alpha enzyme activated podophyllotoxin derivative and preparation method and application thereof | 遵义医药高等专科学校 | 2021-12-28 | — | — | CN | disclosed |
| US-10377774-B2 | Vinblastine derivatives, preparation method therefor and application thereof | JINAN UNIVERSITY (CN) | 2019-08-13 | — | — | US | disclosed |
| EP-2516666-B1 | METHODS OF DETECTING MICROORGANISMS AND KITS THEREFORE | 3M INNOVATIVE PROPERTIES CO (US) | 2016-04-20 | — | — | EP | disclosed |
| US-6566508-B2 | Compound for use in the accurate detection of food parasites | 3M INNOVATIVE PROPERTIES COMPANY | 2003-05-20 | — | — | US | disclosed |
| US-20020147317-A1 | Fluorogenic compounds and uses therefor | 3M INNOVATIVE PROPETIES COMPANY | 2002-10-10 | — | — | US | disclosed |
| US-6372895-B1 | USEFUL IN ASSAYING FOR BIOLOGICAL ACTIVITY | 3M INNOVATIVE PROPERTIES COMPANY | 2002-04-16 | — | — | US | disclosed |
| US-5219741-A | Reacting in the presence of microbiologically produced N-acyl-L-proline acylase | DEGUSSA AG (DE) | 1993-06-15 | — | — | US | disclosed |
| US-5120652-A | Synthesis of proline from acyl derivatives; thermostable | DEGUSSA AG (DE) | 1992-06-09 | — | — | US | disclosed |
| JP-S6474987-A | NOVEL PROLINE ACYLASE AND ITS PRODUCTION | DAICEL CHEM | 1989-03-20 | — | — | JP | disclosed |
| JP-S06474987-A | — | — | 0001-01-01 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020147317-A1 | Fluorogenic compounds and uses therefor | NOTUM, WEE1, CPSF7 | ALDH1A1 762/4885HTR2C 3952/4885HTR2B 3959/4885 |
| US-10377774-B2 | Vinblastine derivatives, preparation method therefor and application thereof | WEE1, WEE2, VIP | ALDH1A1 1008/4885HTR2C 4741/4885HTR2B 4602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.