Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CTSC | P53634 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PREP | P48147 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2228391 | 0.87 | ALDH1A1 (0.55) | HTR2CHTR2BTSHRCTSCALDH1A1 | |
| SCHEMBL23630151 | 0.84 | ALDH1A1 (0.56) | HTR2CHTR2BTSHRALDH1A1MAPK1 | |
| SCHEMBL4758450 | 0.83 | TSHR (0.51) | HTR2CHTR2BTSHRGLACTSC | |
| SCHEMBL3447413 | 0.83 | TSHR (0.51) | HTR2CHTR2BTSHRGLACTSC | |
| SCHEMBL489770 | 0.83 | TSHR (0.51) | HTR2CHTR2BTSHRGLACTSC | |
| SCHEMBL4069956 | 0.82 | TSHR (0.63) | HTR2CHTR2BTSHRGLACTSC | |
| SCHEMBL630517 | 0.82 | TSHR (0.63) | HTR2CHTR2BTSHRGLACTSC | |
| SCHEMBL693351 | 0.82 | TSHR (0.63) | HTR2CHTR2BTSHRGLACTSC | |
| SCHEMBL8134913 | 0.82 | HTR2C (0.63) | HTR2CHTR2BTSHRGLACTSC | |
| SCHEMBL8773302 | 0.82 | HTR2C (0.63) | HTR2CHTR2BTSHRGLACTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4514391-A | HYPOTENSIVE AGENTS; ANALGESICS | E. R. SQUIBB & SONS, INC. (US) | 1985-04-30 | — | — | US | disclosed |
| EP-0132304-A2 | Hydroxy substituted peptide compounds | E.R. Squibb & Sons, Inc. (US) | 1985-01-30 | — | — | EP | disclosed |