Sorbic Acid

Sorbic Acid

SCHEMBL22284124

C/C=C/C=C/C(=O)[O-].C/C=C/C=C/C(=O)[O-].C/C=C/C=C/C(=O)[O-].[Ca+2].[Na+]

nearest known ligand 0.50

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Known targets — ChEMBL curated mechanism

GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Sorbic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA4 P22748 2/20 0.36
BBOX1 O75936 1/20 0.34
CA1 P00915 2/20 0.33
ALDH1A1 P00352 1/20 0.33
CNR2 P34972 6/20 0.32
CNR1 P21554 4/20 0.32
PPARG P37231 1/20 0.32
PPARD Q03181 1/20 0.32
PPARA Q07869 1/20 0.32
CA9 Q16790 1/20 0.31
RAB9A P51151 1/20 0.31
TRPA1 O75762 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sorbic Acid SCHEMBL1759655 1.00 CA4 (0.36) CA4BBOX1CA1ALDH1A1CNR2
Sorbic Acid SCHEMBL2353831 0.97 CA4 (0.38) CA4BBOX1CA1ALDH1A1CNR2
Sorbic Acid SCHEMBL28680231 0.97 CA4 (0.38) CA4BBOX1CA1ALDH1A1CNR2
Sorbic Acid SCHEMBL41692 0.97
Sorbic Acid SCHEMBL29963629 0.97 CA4 (0.38) CA4BBOX1CA1ALDH1A1CNR2
Sorbic Acid SCHEMBL41693 0.97
Sorbic Acid SCHEMBL146360 0.97 BBOX1 (0.36) CA4BBOX1CA1ALDH1A1CNR2
Sorbic Acid SCHEMBL146359 0.97 BBOX1 (0.36) CA4BBOX1CA1ALDH1A1CNR2
Sorbic Acid SCHEMBL27789796 0.97 BBOX1 (0.36) CA4BBOX1CA1ALDH1A1CNR2
Sorbic Acid SCHEMBL5328357 0.95 CA4 (0.43) CA4BBOX1CA1ALDH1A1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024128333-A1 COMPOSITION USING VERATRUM VERSICOLOR EXTRACT FOR REDUCING SKIN WRINKLES AND WHITENING SKIN 주식회사 뉴셀팜 2024-06-20 WO disclosed
WO-2023224134-A1 COMPOSITION FOR IMPROVING COGNITIVE ABILITY USING WATER SOLUBLE CURCUMIN AND BOSWELLIA EXTRACTS 주식회사 다미래 2023-11-23 WO disclosed
CN-115667493-A Novel radioresistant deinococcus strains, exopolysaccharides derived therefrom and compositions containing same 韩国原子力研究院 2023-01-31 CN disclosed
CN-114729335-A Mono-or dihydroxy derivatives of polyunsaturated fatty acids, method for the production thereof and use thereof 韩国生命工学研究院 2022-07-08 CN disclosed
US-11191746-B2 Composition for inhibiting a growth of cancer stem cells comprising ciclesonide JEJU NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2021-12-07 US disclosed
CN-111989399-A Process for preparing polyhydroxy derivatives of polyunsaturated fatty acids 韩国生命工学研究院 2020-11-24 CN disclosed
US-20200246307-A1 COMPOSITION FOR INHIBITING A GROWTH OF CANCER STEM CELLS COMPRISING CICLESONIDE JEJU NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2020-08-06 US disclosed
CN-110366419-A Composition for inhibiting side effects of cytotoxic anticancer agent using ginsenoside compound K 恩进生物科技有限公司 2019-10-22 CN disclosed
CN-103271303-B Method for preparing raw material for functional foods from barley or wheat seeds JEJUHONGAMGA 2014-12-17 CN disclosed
CN-102058067-B Method for preparing raw material for functional food from barley or wheat seeds LEE GYU-GIL 2013-10-30 CN disclosed
CN-103271303-A Method for preparing raw material for functional foods from barley or wheat seeds JEJUHONGAMGA 2013-09-04 CN disclosed
CN-102058067-A Method for preparing raw material for functional food from barley or wheat seeds GYU-GIL LEE 2011-05-18 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11191746-B2 Composition for inhibiting a growth of cancer stem cells comprising ciclesonide STAT3, CD44, MYC CA4 432/4885BBOX1 3704/4885CA1 740/4885
US-20200246307-A1 COMPOSITION FOR INHIBITING A GROWTH OF CANCER STEM CELLS COMPRISING CICLESONIDE STAT3, CD44, MYC CA4 432/4885BBOX1 3704/4885CA1 740/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.