SCHEMBL2228465

SCHEMBL2228465

COC(=O)N[C@@H](CC(C)C)C(=O)NN

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CTSK P43235 4/20 0.44
CTSL P07711 3/20 0.44
CTSS P25774 3/20 0.44
CTSB P07858 2/20 0.44
BIRC2 Q13490 1/20 0.41
ALDH1A1 P00352 1/20 0.40
FOLH1 Q04609 4/20 0.40
ANPEP P15144 1/20 0.39
LAP3 P28838 2/20 0.39
CAPN1 P07384 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2228461 1.00 CTSK (0.44) CTSKCTSLCTSSCTSBBIRC2
SCHEMBL25293909 0.83 CTSK (0.65) CTSKCTSLCTSSCTSBCAPN1
SCHEMBL5557615 0.83 CTSK (0.65) CTSKCTSLCTSSCTSBCAPN1
SCHEMBL7159331 0.83 CTSK (0.65) CTSKCTSLCTSSCTSBCAPN1
SCHEMBL7771103 0.81 ALDH1A1 (0.42) CTSKCTSLCTSSCTSBALDH1A1
SCHEMBL2178778 0.79 CTSK (0.52) CTSKCTSLCTSSCTSBALDH1A1
SCHEMBL12661064 0.79 ALDH1A1 (0.48) CTSKCTSLCTSSCTSBALDH1A1
SCHEMBL8536002 0.79 ALDH1A1 (0.48) CTSKCTSLCTSSCTSBALDH1A1
SCHEMBL3447885 0.79 ALDH1A1 (0.64) ALDH1A1FOLH1LAP3
SCHEMBL11434953 0.79 TAS1R3 (0.54) BIRC2FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011080562-A1 NOVEL AZA-PEPTIDES CONTAINING 2,2-DISUBSTITUTED CYCLOBUTYL AND/OR SUBSTITUTED ALKOXY BENZYL DERIVATIVES AS ANTIVIRALS HETERO RESEARCH FOUNDATION (IN) 2011-07-07 WO disclosed