Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.42 |
| ▸ | HPGDS | O60760 | 2/20 | 0.41 |
| ▸ | LAP3 | P28838 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12661064 | 0.86 | ALDH1A1 (0.48) | ALDH1A1FOLH1LAP3MEN1LMNA | |
| SCHEMBL12500677 | 0.86 | ALDH1A1 (0.48) | ALDH1A1FOLH1LAP3MEN1LMNA | |
| SCHEMBL8536002 | 0.86 | ALDH1A1 (0.48) | ALDH1A1FOLH1LAP3MEN1LMNA | |
| SCHEMBL7883345 | 0.83 | SMN1; SMN2 (0.45) | ALDH1A1FOLH1HPGDSLAP3CNR2 | |
| SCHEMBL7769892 | 0.83 | PPID (0.42) | ALDH1A1FOLH1HPGDSLAP3CTSK | |
| SCHEMBL2632701 | 0.82 | CTSK (0.60) | CTSLCTSBCTSSCTSKCA1 | |
| SCHEMBL14152879 | 0.82 | CTSK (0.60) | CTSLCTSBCTSSCTSKCA1 | |
| SCHEMBL7770030 | 0.82 | KCNA5 (0.40) | ALDH1A1FOLH1HPGDSLAP3CNR2 | |
| SCHEMBL11434953 | 0.82 | TAS1R3 (0.54) | FOLH1TAS1R3TAS1R1 | |
| SCHEMBL3447885 | 0.82 | ALDH1A1 (0.64) | ALDH1A1FOLH1LAP3MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |