Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 6/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | KDM4A | O75164 | 1/20 | 0.57 |
| ▸ | KDM5A | P29375 | 1/20 | 0.57 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.57 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.57 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | REN | P00797 | 1/20 | 0.54 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MC4R | P32245 | 4/20 | 0.49 |
| ▸ | MC5R | P33032 | 4/20 | 0.49 |
| ▸ | MC3R | P41968 | 4/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23120358 | 0.82 | ALOX5 (0.53) | ALOX5GAAHDAC1HDAC6MAPT | |
| SCHEMBL21242365 | 0.81 | HDAC1 (0.59) | ALOX5GAAHDAC1HDAC6REN | |
| SCHEMBL4207867 | 0.81 | HDAC1 (0.57) | ALOX5GAAHDAC1HDAC6REN | |
| SCHEMBL7129964 | 0.81 | ALOX5 (0.66) | ALOX5HDAC1HDAC6KDM4AKDM5A | |
| SCHEMBL2798062 | 0.80 | REN (0.61) | ALOX5GAAHDAC1HDAC6REN | |
| SCHEMBL14224515 | 0.80 | HDAC1 (0.58) | GAAHDAC1HDAC6RENLTB4R2 | |
| SCHEMBL15062810 | 0.80 | KDM4A (0.61) | ALOX5GAAHDAC1HDAC6KDM4A | |
| SCHEMBL8285512 | 0.79 | HDAC1 (0.71) | ALOX5HDAC1HDAC6KDM4AKDM5A | |
| SCHEMBL13965297 | 0.79 | HDAC1 (0.71) | ALOX5HDAC1HDAC6KDM4AKDM5A | |
| SCHEMBL16333819 | 0.78 | REN (0.54) | HDAC1HDAC6RENALDH1A1MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8680263-B2 | Carbohydrate-based drug delivery polymers and conjugates thereof | NEKTAR THERAPEUTICS (US) | 2014-03-25 | — | — | US | disclosed |
| US-20110171716-A1 | CARBOHYDRATE-BASED DRUG DELIVERY POLYMERS AND CONJUGATES THEREOF | NEKTAR THERAPEUTICS (US) | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110171716-A1 | CARBOHYDRATE-BASED DRUG DELIVERY POLYMERS AND CONJUGATES THEREOF | STT3B, STT3A, DDOST | ALOX5 4560/4885GAA 144/4885HDAC1 1382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.