SCHEMBL15062810

SCHEMBL15062810

O=C(O)CN(CCCc1ccccc1)C(=O)CCCCc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4A O75164 1/20 0.61
KDM5A P29375 1/20 0.61
KDM4C Q9H3R0 1/20 0.61
PHF8 Q9UPP1 1/20 0.61
KDM2A Q9Y2K7 1/20 0.61
ALOX5 P09917 6/20 0.59
MAPT P10636 1/20 0.59
RXFP1 Q9HBX9 1/20 0.59
HDAC1 Q13547 4/20 0.53
HDAC2 Q92769 2/20 0.53
HDAC8 Q9BY41 2/20 0.53
HDAC3 O15379 1/20 0.53
MAPK1 P28482 1/20 0.53
ADRA1A P35348 1/20 0.53
HDAC4 P56524 1/20 0.53
SLC6A3 Q01959 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
HDAC7 Q8WUI4 1/20 0.53
HDAC10 Q969S8 1/20 0.53
HDAC11 Q96DB2 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15062794 0.84 ALOX5 (0.56) KDM4AKDM5AKDM4CPHF8KDM2A
SCHEMBL7374440 0.83 ALOX5 (0.58) KDM4AKDM5AKDM4CPHF8KDM2A
SCHEMBL11737741 0.83 NPC1 (0.66) KDM4AKDM5AKDM4CPHF8KDM2A
SCHEMBL2449093 0.81 KEAP1 (0.61) KDM4AKDM5AKDM4CPHF8KDM2A
SCHEMBL7992967 0.81 ALOX5 (0.56) KDM4AKDM5AKDM4CPHF8KDM2A
SCHEMBL2228643 0.80 ALOX5 (0.61) KDM4AKDM5AKDM4CPHF8KDM2A
SCHEMBL7444522 0.80 MAPT (0.68) KDM4AKDM5AKDM4CPHF8KDM2A
SCHEMBL16921495 0.78 ALOX5 (0.49) KDM4AKDM5AKDM4CPHF8KDM2A
SCHEMBL708672 0.78 ADRA1A (0.58) KDM4AKDM5AKDM4CPHF8KDM2A
SCHEMBL10691673 0.77 ALOX5 (0.90) KDM4AKDM5AKDM4CPHF8KDM2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8809012-B2 Labeling agent and methods for simultaneous sequencing and quantification of multiple peptides and proteins using the same Postach Academy-Industry Foundation (KR) 2014-08-19 US claimed
US-20130183704-A1 Labeling Agent and Methods for Simultaneous Sequencing and Quantification of Multiple Peptides and Proteins Using the Same POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) 2013-07-18 US claimed
EP-2610243-A2 LABELING AGENT AND AMINO ACID SEQUENCE USING SAME, AND METHOD FOR PERFORMING SIMULTANEOUS QUANTITATIVE ANALYSIS OF MULTIPLE PROTEINS Postech Academy-industry Foundation (KR) 2013-07-03 EP claimed
US-8809012-B2 Labeling agent and methods for simultaneous sequencing and quantification of multiple peptides and proteins using the same Postach Academy-Industry Foundation (KR) 2014-08-19 US disclosed
US-8809012-B2 Labeling agent and methods for simultaneous sequencing and quantification of multiple peptides and proteins using the same Postach Academy-Industry Foundation (KR) 2014-08-19 US disclosed
US-20130183704-A1 Labeling Agent and Methods for Simultaneous Sequencing and Quantification of Multiple Peptides and Proteins Using the Same POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) 2013-07-18 US disclosed
EP-2610243-A2 LABELING AGENT AND AMINO ACID SEQUENCE USING SAME, AND METHOD FOR PERFORMING SIMULTANEOUS QUANTITATIVE ANALYSIS OF MULTIPLE PROTEINS Postech Academy-industry Foundation (KR) 2013-07-03 EP disclosed
EP-2610243-A2 LABELING AGENT AND AMINO ACID SEQUENCE USING SAME, AND METHOD FOR PERFORMING SIMULTANEOUS QUANTITATIVE ANALYSIS OF MULTIPLE PROTEINS Postech Academy-industry Foundation (KR) 2013-07-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130183704-A1 Labeling Agent and Methods for Simultaneous Sequencing and Quantification of Multiple Peptides and Proteins Using the Same YWHAQ, IAPP, RPS27A KDM4A 1369/4885KDM5A 2287/4885KDM4C 2229/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.