Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4971125 | 0.98 | BACE1 (0.50) | ALDH1A1MEN1CASP1CASP7KMT2A | |
| SCHEMBL31121067 | 0.93 | ALDH1A1 (0.52) | ALDH1A1MEN1CASP1CASP7KMT2A | |
| SCHEMBL3515288 | 0.93 | ALDH1A1 (0.52) | ALDH1A1MEN1CASP1CASP7KMT2A | |
| SCHEMBL17672031 | 0.86 | BACE1 (0.55) | ALDH1A1CASP1HTTBACE1CHRNA7 | |
| SCHEMBL15534906 | 0.85 | QDPR (0.46) | ALDH1A1MEN1CASP1CASP7KMT2A | |
| SCHEMBL11460811 | 0.85 | BACE1 (0.58) | ALDH1A1CASP1HTTBACE1CHRNA7 | |
| SCHEMBL31087555 | 0.85 | BACE1 (0.58) | ALDH1A1CASP1HTTBACE1CHRNA7 | |
| SCHEMBL22857367 | 0.84 | DDB1 (0.48) | ALDH1A1MEN1CASP1CASP7KMT2A | |
| SCHEMBL24870695 | 0.82 | CHRNA7 (0.42) | ALDH1A1MEN1CASP1CASP7KMT2A | |
| SCHEMBL28712870 | 0.82 | ALDH1A1 (0.41) | ALDH1A1MEN1CASP1CASP7KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4083031-B1 | QUINOLINE COMPOUND AND APPLICATION THEREOF AS FGFR4 KINASE INHIBITOR | SKYRUN PHARMA CO LTD (CN) | 2026-04-22 | — | — | EP | disclosed |
| US-20230014962-A1 | Quinoline compound and use thereof | SKYRUN PHARMA CO LTD (CN) | 2023-01-19 | — | — | US | disclosed |
| EP-4083031-A1 | QUINOLINE COMPOUND AND APPLICATION THEREOF | Skyrun Pharma Co., Ltd. (CN) | 2022-11-02 | — | — | EP | disclosed |
| CN-114956933-A | Marker containing isotope oxygen atom and preparation method and application thereof | 清华大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-111517902-B | Aerobic oxidation system containing sulfinic acid, sulfonic acid or derivatives thereof and photo-oxidation promoting method thereof | 清华大学 | 2022-06-14 | — | — | CN | disclosed |
| CN-111517902-A | Aerobic oxidation system containing sulfinic acid, sulfonic acid or derivatives thereof and photo-oxidation promoting method thereof | 清华大学 | 2020-08-11 | — | — | CN | disclosed |
| WO-2020155595-A1 | AEROBIC OXIDATION SYSTEM CONTAINING SULFINIC ACID, SULFONIC ACID OR DERIVATIVES THEREOF AND PHOTOCATALYTIC OXIDATION METHOD THEREFOR | 清华大学 | 2020-08-06 | — | — | WO | disclosed |
| CN-1054845-C | Quinoline compounds | NOVARTIS AG (CH) | 2000-07-26 | — | — | CN | disclosed |
| CN-1105991-A | Quinoline compounds | CIBA GEIGY AG (CH) | 1995-08-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230014962-A1 | Quinoline compound and use thereof | FGFR4, FGFR1, FGFR3 | ALDH1A1 1995/4885MEN1 2636/4885CASP1 2829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.