Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22288192 | 0.98 | ALDH1A1 (0.49) | BACE1ALDH1A1MEN1CASP1CASP7 | |
| SCHEMBL3515288 | 0.91 | ALDH1A1 (0.52) | ALDH1A1MEN1CASP1CASP7KMT2A | |
| SCHEMBL31121067 | 0.91 | ALDH1A1 (0.52) | ALDH1A1MEN1CASP1CASP7KMT2A | |
| SCHEMBL11460811 | 0.87 | BACE1 (0.58) | BACE1ALDH1A1CASP1HTTCYP11B2 | |
| SCHEMBL31087555 | 0.87 | BACE1 (0.58) | BACE1ALDH1A1CASP1HTTCYP11B2 | |
| SCHEMBL17672031 | 0.85 | BACE1 (0.55) | BACE1ALDH1A1CASP1HTTCYP11B2 | |
| SCHEMBL24870695 | 0.84 | CHRNA7 (0.42) | ALDH1A1MEN1CASP1CASP7KMT2A | |
| SCHEMBL15534906 | 0.84 | QDPR (0.46) | ALDH1A1MEN1CASP1CASP7KMT2A | |
| SCHEMBL22857367 | 0.83 | DDB1 (0.48) | ALDH1A1MEN1CASP1CASP7KMT2A | |
| SCHEMBL28706150 | 0.80 | ESR1 (0.47) | ALDH1A1MEN1CASP1CASP7KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1969051-A2 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | N.V. Organon (NL) | 2008-09-17 | — | — | EP | disclosed |
| WO-2007079180-A2 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | N.V. ORGANON (NL) | 2007-07-12 | — | — | WO | disclosed |