Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.52 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31121067 | 1.00 | ALDH1A1 (0.52) | ALDH1A1MEN1CASP1CASP7KMT2A | |
| SCHEMBL22288192 | 0.93 | ALDH1A1 (0.49) | ALDH1A1MEN1CASP1CASP7KMT2A | |
| SCHEMBL4971125 | 0.91 | BACE1 (0.50) | ALDH1A1MEN1CASP1CASP7KMT2A | |
| SCHEMBL15534906 | 0.89 | QDPR (0.46) | ALDH1A1MEN1CASP1CASP7KMT2A | |
| SCHEMBL28706150 | 0.88 | ESR1 (0.47) | ALDH1A1MEN1CASP1CASP7KMT2A | |
| SCHEMBL28712870 | 0.88 | ALDH1A1 (0.41) | ALDH1A1MEN1CASP1CASP7KMT2A | |
| SCHEMBL22857367 | 0.87 | DDB1 (0.48) | ALDH1A1MEN1CASP1CASP7KMT2A | |
| SCHEMBL29940279 | 0.85 | IDO1 (0.57) | ALDH1A1MEN1CASP1KMT2AHTT | |
| SCHEMBL28286305 | 0.85 | IDO1 (0.57) | ALDH1A1MEN1CASP1KMT2AHTT | |
| SCHEMBL24869912 | 0.82 | SLC6A2 (0.49) | ALDH1A1MEN1CASP1CASP7KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8853202-B2 | Modulators of CXCR7 | CHEMOCENTRYX, INC. (US) | 2014-10-07 | — | — | US | disclosed |
| US-20100311712-A1 | MODULATORS OF CXCR7 | CHEMOCENTRYX, INC. (US) | 2010-12-09 | — | — | US | disclosed |
| US-20100311712-A1 | MODULATORS OF CXCR7 | CHEMOCENTRYX, INC. (US) | 2010-12-09 | — | — | US | disclosed |
| US-20100311712-A1 | MODULATORS OF CXCR7 | CHEMOCENTRYX, INC. (US) | 2010-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100311712-A1 | MODULATORS OF CXCR7 | CXCR1, CXCR5, CCR7 | ALDH1A1 1777/4885MEN1 3638/4885CASP1 2817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.