SCHEMBL22288752

SCHEMBL22288752

O=S(=O)(Cc1ccccc1)Cc1cccc(SSCc2ccc(F)cc2)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.40
BCHE P06276 1/20 0.36
ACHE P22303 1/20 0.36
FAAH O00519 1/20 0.36
PRSS1 P07477 1/20 0.36
PRSS2 P07478 1/20 0.36
ELANE P08246 1/20 0.36
PRTN3 P24158 1/20 0.36
PRSS3 P35030 1/20 0.36
KCNA5 P22460 1/20 0.35
ALDH1A1 P00352 3/20 0.34
CYP19A1 P11511 1/20 0.34
GAA P10253 1/20 0.34
EPHX1 P07099 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
USP2 O75604 1/20 0.34
LMNA P02545 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
CTSB P07858 1/20 0.34
TAAR1 Q96RJ0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22288776 0.92 CA2 (0.38) KMT2ABCHEACHEFAAHPRSS1
SCHEMBL28638050 0.86 L3MBTL1 (0.41) KMT2ABCHEACHEALDH1A1CYP19A1
SCHEMBL22288882 0.85 BCHE (0.39) KMT2ABCHEACHEALDH1A1GAA
SCHEMBL22288748 0.84 HTT (0.46) KMT2ABCHEACHEALDH1A1CYP19A1
SCHEMBL22288515 0.82 L3MBTL1 (0.38) KMT2ABCHEACHEKCNA5ALDH1A1
SCHEMBL22315707 0.82 POLB (0.38) KMT2AALDH1A1EPHX1SMN1; SMN2LMNA
SCHEMBL776238 0.78 SMN1; SMN2 (0.42) ALDH1A1EPHX1SMN1; SMN2LMNACTSB
SCHEMBL22316955 0.76 CTSB (0.32) BCHEACHEALDH1A1EPHX1SMN1; SMN2
SCHEMBL22288891 0.76 ALDH1A1 (0.40) KMT2AFAAHPRSS1PRSS2ELANE
SCHEMBL22288434 0.76 ALDH1A1 (0.41) KMT2AFAAHPRSS1PRSS2ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3917909-A1 DISULPHIDE COMPOUNDS Neem Biotech Limited (GB) 2021-12-08 EP disclosed
CN-113382981-A Disulfide compounds 尼姆生物科技有限公司 2021-09-10 CN disclosed
WO-2020157463-A1 DISULPHIDE COMPOUNDS NEEM BIOTECH LIMITED (GB) 2020-08-06 WO disclosed
WO-2020157463-A1 DISULPHIDE COMPOUNDS NEEM BIOTECH LIMITED (GB) 2020-08-06 WO disclosed