Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 15/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22288646 | 0.85 | PDE3B (0.52) | LMNANPY1RNPY2RMAOBPDE3B | |
| SCHEMBL22288973 | 0.80 | LMNA (0.41) | LMNANPY1RNPY2RMAOBMAPT | |
| SCHEMBL22304685 | 0.80 | PDE3B (0.58) | MAOBPDE3BPDE3A | |
| SCHEMBL22304780 | 0.78 | MAOB (0.45) | MAOBPDE3BPDE3AMAPT | |
| SCHEMBL22288923 | 0.76 | PDE3B (0.57) | MAOBPDE3BPDE3A | |
| SCHEMBL22288953 | 0.75 | PDE3B (0.56) | MAOBPDE3BPDE3A | |
| SCHEMBL22304871 | 0.75 | PDE3B (0.47) | MAOBPDE3BPDE3A | |
| SCHEMBL22304512 | 0.74 | PDE3B (0.46) | MAOBPDE3BPDE3A | |
| SCHEMBL22288920 | 0.73 | PDE3B (0.47) | MAOBPDE3BPDE3A | |
| SCHEMBL22288642 | 0.73 | MAOB (0.44) | MAOBPDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020157201-A1 | OXADIAZINONE COMPOUNDS FOR THE TREATMENT OF HYPERPROLIFERATIVE DISEASES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-08-06 | — | — | WO | disclosed |