Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 17/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22288646 | 0.82 | PDE3B (0.52) | LMNANPY1RNPY2RMAOB | |
| SCHEMBL22288971 | 0.80 | LMNA (0.40) | LMNANPY1RNPY2RMAOBMAPT | |
| SCHEMBL22304780 | 0.79 | MAOB (0.45) | MAOBMAPT | |
| SCHEMBL22304685 | 0.77 | PDE3B (0.58) | MAOB | |
| SCHEMBL22288642 | 0.74 | MAOB (0.44) | MAOB | |
| SCHEMBL22288953 | 0.74 | PDE3B (0.56) | MAOB | |
| SCHEMBL22304871 | 0.72 | PDE3B (0.47) | MAOB | |
| SCHEMBL22304512 | 0.71 | PDE3B (0.46) | MAOB | |
| SCHEMBL22304679 | 0.70 | PDE3B (0.48) | MAOB | |
| SCHEMBL22288923 | 0.70 | PDE3B (0.57) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020157201-A1 | OXADIAZINONE COMPOUNDS FOR THE TREATMENT OF HYPERPROLIFERATIVE DISEASES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-08-06 | — | — | WO | disclosed |