Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 12/20 | 0.50 |
| ▸ | PPARA | Q07869 | 10/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28160043 | 1.00 | ADAMTS5 (0.54) | ADAMTS5MMP2KMT2ACA2PPARG | |
| SCHEMBL5022525 | 0.85 | CA2 (0.54) | ADAMTS5MMP2KMT2ACA2PPARG | |
| SCHEMBL27699871 | 0.85 | CA2 (0.54) | ADAMTS5MMP2KMT2ACA2PPARG | |
| SCHEMBL29964738 | 0.84 | ALDH1A1 (0.57) | KMT2ACA2PPARGPPARAALDH1A1 | |
| SCHEMBL22290826 | 0.84 | ALDH1A1 (0.57) | KMT2ACA2PPARGPPARAALDH1A1 | |
| SCHEMBL1008925 | 0.84 | FOLH1 (0.56) | KMT2ACA2 | |
| SCHEMBL1008926 | 0.84 | FOLH1 (0.56) | KMT2ACA2 | |
| SCHEMBL144008 | 0.83 | MME (0.57) | MMP2ALDH1A1 | |
| SCHEMBL199980 | 0.83 | MME (0.57) | MMP2ALDH1A1 | |
| SCHEMBL31345792 | 0.83 | MME (0.57) | MMP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3917944-A1 | THERAPEUTIC PEPTIDES | Cohbar Inc. (US) | 2021-12-08 | — | — | EP | disclosed |
| WO-2020160003-A1 | THERAPEUTIC PEPTIDES | COHBAR, INC. (US) | 2020-08-06 | — | — | WO | disclosed |
| CN-106999536-A | Macrocyclic inhibitors of PD-1/PD-L1 and CD80(B7-1)/PD-L1 protein/protein interactions | 百时美施贵宝公司 | 2017-08-01 | — | — | CN | disclosed |