Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.37 |
| ▸ | S100A4 | P26447 | 2/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22291912 | 0.87 | CCNA2 (0.37) | ALDH1A1NPSR1EPHX2CCNA2CDK2 | |
| SCHEMBL7943962 | 0.81 | S100A4 (0.43) | ALDH1A1S100A4PTPRCKMT2AMEN1 | |
| SCHEMBL22291965 | 0.81 | TNF (0.42) | ALDH1A1EPHX2KMT2AMEN1DDB1 | |
| SCHEMBL20507500 | 0.78 | KMT2A (0.39) | ALDH1A1NPSR1S100A4PTPRCKMT2A | |
| SCHEMBL29802841 | 0.78 | KMT2A (0.39) | ALDH1A1NPSR1S100A4PTPRCKMT2A | |
| SCHEMBL9935445 | 0.76 | S100A4 (0.41) | ALDH1A1S100A4PTPRCKMT2AMEN1 | |
| SCHEMBL22291976 | 0.75 | DDB1 (0.35) | ALDH1A1S100A4PTPRCKMT2AMEN1 | |
| SCHEMBL22661257 | 0.75 | L3MBTL1 (0.36) | ALDH1A1NPSR1S100A4KMT2AMEN1 | |
| SCHEMBL20507431 | 0.75 | KMT2A (0.48) | ALDH1A1EPHX2KMT2AMEN1MAPT | |
| SCHEMBL22661258 | 0.74 | ALDH1A1 (0.34) | ALDH1A1NPSR1CCNA2CDK2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10730835-B2 | Thalidomide analogs and methods of use | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, HEALTH AND HUMAN SERVICES (US) | 2020-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10730835-B2 | Thalidomide analogs and methods of use | PGF, TYMP, TPMT | ALDH1A1 380/4885NPSR1 3609/4885EPHX2 925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.