Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.57 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.42 |
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.42 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.42 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.42 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2994684 | 0.98 | USP2 (0.67) | USP2HTTSPHK1LPAR5CYP1A2 | |
| SCHEMBL578059 | 0.98 | USP2 (0.67) | USP2HTTSPHK1LPAR5CYP1A2 | |
| SCHEMBL3968392 | 0.98 | USP2 (0.67) | USP2HTTSPHK1LPAR5CYP1A2 | |
| SCHEMBL12802300 | 0.98 | USP2 (0.67) | USP2HTTSPHK1LPAR5CYP1A2 | |
| SCHEMBL2981072 | 0.98 | USP2 (0.67) | USP2HTTSPHK1LPAR5CYP1A2 | |
| SCHEMBL3964904 | 0.98 | USP2 (0.67) | USP2HTTSPHK1LPAR5CYP1A2 | |
| SCHEMBL2988607 | 0.98 | USP2 (0.67) | USP2HTTSPHK1LPAR5CYP1A2 | |
| SCHEMBL8454480 | 0.98 | USP2 (0.67) | USP2HTTSPHK1LPAR5CYP1A2 | |
| SCHEMBL258455 | 0.90 | USP2 (0.55) | USP2HTTSPHK1LPAR5CYP1A2 | |
| SCHEMBL14339072 | 0.89 | USP2 (0.56) | USP2HTTSPHK1LPAR5LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024157751-A1 | OIL-IN-WATER TYPE SOLID COSMETIC | 株式会社資生堂 | 2024-08-02 | — | — | WO | disclosed |
| CN-111263630-B | Oil-in-water type emulsified solid cosmetic | 株式会社资生堂 | 2023-12-08 | — | — | CN | disclosed |
| CN-115531248-A | Oil-in-water type emulsified solid cosmetic | 株式会社资生堂 | 2022-12-30 | — | — | CN | disclosed |
| US-11266579-B2 | Oil-in-water type emulsion solid cosmetic | SHISEIDO COMPANY, LTD. (JP) | 2022-03-08 | — | — | US | disclosed |
| US-20200315929-A1 | OIL-IN-WATER TYPE EMULSION SOLID COSMETIC | SHISEIDO COMPANY, LTD. (JP) | 2020-10-08 | — | — | US | disclosed |
| EP-3705111-A1 | OIL-IN-WATER TYPE EMULSION SOLID COSMETIC | Shiseido Company, Ltd. (JP) | 2020-09-09 | — | — | EP | disclosed |
| US-9539444-B2 | Hair conditioning composition and low energy method of producing the same | SHISEIDO COMPANY, LTD. (JP) | 2017-01-10 | — | — | US | disclosed |
| EP-2394632-A1 | HAIR CONDITIONER COMPOSITION AND LOW-ENERGY MANUFACTURING METHOD FOR THE SAME | Shiseido Co., Ltd. (JP) | 2011-12-14 | — | — | EP | disclosed |
| US-20110165110-A1 | Hair Conditioning Composition And Low Energy Method Of Producing The Same | SHISEIDO COMPANY, LTD. (JP) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11266579-B2 | Oil-in-water type emulsion solid cosmetic | CUTA, MUC1, SMARCA1 | USP2 2624/4885HTT 1740/4885SPHK1 2416/4885 |
| US-20110165110-A1 | Hair Conditioning Composition And Low Energy Method Of Producing The Same | CUTA, POLR1C, TIMCC | USP2 3972/4885HTT 3280/4885SPHK1 365/4885 |
| US-20200315929-A1 | OIL-IN-WATER TYPE EMULSION SOLID COSMETIC | CUTA, MUC1, SMARCA1 | USP2 2624/4885HTT 1740/4885SPHK1 2416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.