Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | WDR5 | P61964 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12829856 | 1.00 | MAPT (0.35) | MAPTALDH1A1HPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL18506199 | 0.97 | MEN1 (0.34) | MAPTALDH1A1HPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL10065953 | 0.92 | TRPM8 (0.35) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL19707096 | 0.89 | LTB4R2 (0.35) | MAPTHPGDMEN1KMT2ALMNA | |
| SCHEMBL18533905 | 0.87 | PIN1 (0.35) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL23221626 | 0.86 | ALDH1A1 (0.40) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL22099639 | 0.83 | — | — | |
| SCHEMBL18801297 | 0.83 | — | — | |
| SCHEMBL20466593 | 0.83 | MAPT (0.33) | MAPTALDH1A1HPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL24023059 | 0.82 | MAPT (0.41) | MAPTALDH1A1HPGDSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3689882-A1 | NEW MATERIALS WITH AZA-DIBENZOTHIOPHENE OR AZA-DIBENZOFURAN CORE FOR PHOLED | Universal Display Corporation (US) | 2020-08-05 | — | — | EP | disclosed |