Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18506199 | 0.89 | MEN1 (0.34) | ALDH1A1MAPK1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL12829856 | 0.86 | MAPT (0.35) | ALDH1A1MAPK1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL22294815 | 0.86 | MAPT (0.35) | ALDH1A1MAPK1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL10065953 | 0.85 | TRPM8 (0.35) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL19707096 | 0.81 | LTB4R2 (0.35) | MEN1KMT2AGAAMAPT | |
| SCHEMBL24633200 | 0.79 | LIPG (0.52) | — | |
| SCHEMBL18801297 | 0.78 | — | — | |
| SCHEMBL13175367 | 0.77 | ABCG2 (0.30) | — | |
| SCHEMBL17751427 | 0.76 | — | — | |
| SCHEMBL22036430 | 0.76 | SLC6A9 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3806176-A1 | ELECTRONIC DEVICE | Merck Patent GmbH (DE) | 2021-04-14 | — | — | EP | disclosed |